Evidence map›Paper›PMID 35451705›Full record

ArticleParasitology research2022

Outbreak of Cryptosporidium hominis in northern Sweden: persisting symptoms in a 5-year follow-up.

Malin Sjöström, M Arvidsson, L Söderström, M Lilja, J Lindh, M Widerström

Abstract read
In one paragraph

Article in Parasitology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Current research in parasitology & vector-borne diseases · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Malin SjöströmDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden. malin.sjostrom@umu.se.ORCID http://orcid.org/0000-0003-0868-6249
M ArvidssonDepartment of Clinical Microbiology, Umeå University, Umeå, Sweden.
L SöderströmUnit of Research, Education and Development-Östersund Hospital, Östersund, Sweden.
M LiljaDepartment of Public Health and Clinical Medicine, Unit of Research, Education, and Development, Östersund Hospital, Umeå University, Umeå, Sweden.
J LindhDepartment of Cell and Molecular Biology, BMC, Uppsala University, Uppsala, Sweden.
M WiderströmDepartment of Clinical Microbiology, Umeå University, Umeå, Sweden.

Funding

County Council Jämtland Härjedalen JLL-564341
6 · The paper itself

Abstract

In 2010-2011, a waterborne outbreak of the parasite, Cryptosporidium hominis, affected approximately 27,000 inhabitants in the city of Östersund, Sweden. Previous research suggested that post-infectious symptoms, such as gastrointestinal symptoms and joint pain, could persist for up to 2 years after the initial infection. In this study, we investigated whether the parasite caused post-infectious sequelae for up to 5 years after the outbreak. Prospective cohort study. A randomly selected cohort of individuals residing in Östersund at the time of the outbreak was sent a postal questionnaire in 2011. Responders were sent a follow-up questionnaire in 2016 and completed items on whether they experienced a list of symptoms. We examined whether outbreak cases were more likely than non-cases to report post-infectious symptoms 5 years later. We analysed data using logistic regression and calculated odds ratios with 95% confidence intervals. The analysis included 626 individuals. Among the 262 individuals infected during the outbreak, 56.5% reported symptoms at follow-up. Compared to non-cases, outbreak cases were more likely to report watery diarrhoea, diarrhoea, swollen joints, abdominal pain, bloating, joint discomfort, acid indigestion, alternating bowel habits, joint pain, ocular pain, nausea, and fatigue at the follow-up, after adjusting for age and sex. Our findings suggested that cryptosporidiosis was mainly associated with gastrointestinal- and joint-related post-infectious symptoms for up to 5 years after the infection.

Indexed as

CryptosporidiosisCryptosporidiumArthralgiaDiarrheaDisease OutbreaksFollow-Up StudiesHumansProspective StudiesSwedenCryptosporidiumDiarrhoeaDisease outbreaksPost-infectious symptomsSequelae

Identifiers

PMID35451705
PMCPMC9192462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.