Evidence map›Paper›PMID 35451619›Full record

ArticleAnnals of hematology2022

Congenital asplenia study: clinical and laboratory characterisation of adults with congenital asplenia.

Grace I Butel-Simoes, Penelope Jones, Erica M Wood, Denis Spelman, Ian J Woolley, Samar Ojaimi

Abstract read
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In one paragraph

Article in Annals of hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Grace I Butel-SimoesMonash Infectious Diseases, Monash Health, Victoria, Australia. gbutelsimoes@gmail.com.
Penelope JonesSpleen Australia, Alfred Health, Victoria, Australia.
Erica M WoodSchool of Public Health and Preventive Medicine, Monash University, Victoria, Australia.
Denis SpelmanSpleen Australia, Alfred Health, Victoria, Australia.
Ian J WoolleyMonash Infectious Diseases, Monash Health, Victoria, Australia.
Samar OjaimiMonash Infectious Diseases, Monash Health, Victoria, Australia.
Monash Health · AUAlfred Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital asplenia is a rare disorder commonly associated with other visceral and cardiac congenital anomalies. Isolated congenital asplenia is even less common than syndromic forms. The risk of severe bacterial infections associated with asplenia is the most concerning clinical implication and carries a significant mortality risk. Prophylactic measures against the clinical syndrome known as overwhelming postsplenectomy infections (OPSI) include vaccination, prophylactic and emergency antibiotics and health education including fever management and travel advice. This case series describes fourteen adults with congenital asplenia and polysplenia syndrome, most of whom were diagnosed incidentally as adults, and outlines the nature of their diagnosis, clinical phenotype, family history and key pathology findings.

Indexed as

Splenic DiseasesAnti-Bacterial AgentsHumansSyndromeVaccinationAnti-Bacterial AgentsCongenital aspleniaCongenital polyspleniaHowell-Jolly bodiesSpleen

Identifiers

PMID35451619
OpenAlexW4224215998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.