ArticleAnimal genetics2022
Identification of two new recessive MC1R alleles in red-coloured Evolèner cattle and other breeds.
Article in Animal genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Integrating landscape genomics and machine learning to analyze the genetic structure and specific molecular markers of Chinese dairy goats (Capra hircus).Journal of animal science and biotechnology · 2026Article
- Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds.Animal genetics · 2026Article
- Associations of MC1R Substitutions With Body Color Variation in a Desert Lizard.Ecology and evolution · 2026Article
- The Genomic Landscape of Cattle: Domestication, Dispersal, and Adaptive Evolution.Animals : an open access journal from MDPI · 2026Review
- A recessive coat color dilution in Dexter cattle attributed to a missense mutation in SLC45A2.Animal genetics · 2025Article
- Detection ofAnimals : an open access journal from MDPI · 2025Article
- Identification of two new recessive MC1R alleles in red-coloured Evolèner cattle and other breeds.Animal genetics · 2022Article
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Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sequence variations in the melanocortin-1 receptor (MC1R) gene are associated with melanism in different animal species. Six functionally relevant alleles have been described in cattle to date. In a hypothesis-free approach we performed a genome-wide allelic association study with black, red and wild-coloured cattle of three Alpine cattle breeds (Eringer, Evolèner and Valdostana), revealing a single significant association signal close to the MC1R gene. We searched for candidate causative variants by sequencing the entire coding sequence and identified two novel protein-changing variants. We propose designating the mutant alleles at MC1R:c.424C>T as e
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