Evidence map›Paper›PMID 35451351›Full record

Trial reportThe journal of vascular access2024

Arteriovenous fistula creation with VasQ

Michela Bozzetto, Luca Soliveri, Sofia Poloni, Paolo Brambilla, Diego Curtò, Giuseppina Carmela Condemi, Pietro Cefalì, Irene Spina, Alessandro Villa, Anna Caroli and 1 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of vascular access, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Michela BozzettoDepartment of Engineering and Applied Sciences, University of Bergamo, Italy.ORCID 0000-0002-2045-5550
Luca SoliveriDepartment of Biomedical Engineering - Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Sofia PoloniDepartment of Biomedical Engineering - Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.ORCID 0000-0002-9402-9925
Paolo BrambillaDiagnostic Radiology, Papa Giovanni XXIII Hospital, University of Milano-Bicocca, Milan, Italy.
Diego CurtòUnit of Nephrology and Dialysis, ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Giuseppina Carmela CondemiUnit of Nephrology and Dialysis, ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Pietro CefalìUnit of Vascular Surgery, ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Irene SpinaUnit of Vascular Surgery, ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Alessandro VillaDepartment of Renal Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.ORCID 0000-0001-5556-5701
Anna CaroliDepartment of Biomedical Engineering - Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Andrea RemuzziDepartment of Management, Information and Production Engineering, University of Bergamo, Italy.ORCID 0000-0002-4301-8927
Ospedale Papa Giovanni XXIII · ITMario Negri Institute for Pharmacological Research · ITUniversity of Bergamo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArteriovenous fistula (AVF) is the preferred vascular access (VA) for hemodialysis, but it is still affected by high non-maturation and early failure rates due to stenosis development. Increasing evidence suggests that the presence of turbulent-like flow may play a key role, therefore, to stabilize the flow in the venous segment, an external support device (VasQ

methodsIn this pilot single-center prospective randomized study six patients were enrolled, three in the VasQ group and three in the control group. Contrast-free magnetic resonance imaging (MRI) scans were acquired at 3 days, 3 months and 1 year after AVF surgery and were used to generate 3D patient-specific models. Computational fluid dynamic (CFD) simulations were performed using pimpleFoam, imposing patient-specific flow waveforms derived from ultrasound (US) examinations at the inlet of the proximal and distal artery, and a traction-free condition at the venous outflow. Morphologic and hemodynamic changes occurring over time were compared between VasQ and control AVFs.

resultsOur MRI protocol provided high-quality images suitable for reliable segmentation and reconstruction of patient-specific 3D models of AVFs at all three timepoints in four out of six patients. The VasQ

conclusionsThis study demonstrated the feasibility of characterizing the morphological and hemodynamic changes occurring over time in AVFs created using the VasQ

Indexed as

Arteriovenous FistulaArteriovenous Shunt, SurgicalConstriction, PathologicFeasibility StudiesHemodynamicsHumansPilot ProjectsProspective StudiesRenal DialysisVascular PatencyArteriovenous fistulacomputational fluid dynamicsdisturbed flowexternal support devicelongitudinal changes

Identifiers

PMID35451351
PMCPMC10845834
OpenAlexW4224237101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.