Evidence map›Paper›PMID 35451112›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2022

Comparative study shows that 1 in 7 Spanish children with COVID-19 symptoms were still experiencing issues after 12 weeks.

María Bergia, Elena Sanchez-Marcos, Blanca Gonzalez-Haba, Ana I Hernaiz, María de Ceano-Vivas, Milagros García López-Hortelano, Mª Luz García-García, Raquel Jimenez-García, Cristina Calvo

Abstract readMulticenter Study
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

María BergiaPediatrics and Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.
Elena Sanchez-MarcosPediatrics Department, Niño Jesús University Hospital, Madrid, Spain.
Blanca Gonzalez-HabaPediatrics and Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.
Ana I HernaizHernáiz A. MD. Alfonso X El Sabio University, Madrid, Spain.
María de Ceano-VivasPediatrics Emergency Department, La Paz University Hospital, Madrid, Spain.
Milagros García López-HortelanoPediatrics and Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.
Mª Luz García-GarcíaTraslational Research Network of Pediatric Infectious Diseases (RITIP), Madrid, Spain.
Raquel Jimenez-GarcíaPediatrics Department, Niño Jesús University Hospital, Madrid, Spain.
Cristina CalvoPediatrics and Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.ORCID 0000-0002-6503-3423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe investigated prolonged symptoms in children after COVID-19, including the clinical characteristics and risk factors.

methodsThis multicentre retrospective study focused on 451 children under 18 years old who were diagnosed with symptomatic COVID-19 between 14 March and 31 December 2020. Persistent symptoms were analysed with a telephone questionnaire by the attending physicians from 1 August to 30 September 2021. A control group of 98 with no history of COVID-19, who were treated for other reasons, was also included.

resultsMost (82.0%) of the cases had mild infections that required outpatient care and 5.1% were admitted to the paediatric intensive care unit (PICU). We found that 18.4% had symptoms that lasted 4-12 weeks. There were also 14.6% who were symptomatic for longer than 12 weeks and the odds risks were higher for children aged 5 years or more (OR 3.0), hospitalised (OR 3.9), admitted to the PICU (OR 4.3) and with relatives who were symptomatic for 12 weeks or more (OR 2.8). The controls had similar percentages of prolonged symptoms, despite having no history of COVID-19, especially those who were older than 5 years.

conclusionThis study confirmed that a worrying percentage of children had prolonged symptoms after COVID-19.

Indexed as

COVID-19AdolescentChildHospitalizationHumansIntensive Care Units, PediatricRetrospective StudiesSARS-CoV-2childrenmulticentre studypandemicpost-COVID-19questionnaire

Identifiers

PMID35451112
PMCPMC9111513

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.