Evidence map›Paper›PMID 35450958›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Staging Liver Fibrosis by Fibroblast Activation Protein Inhibitor PET in a Human-Sized Swine Model.

Ali Pirasteh, Sarvesh Periyasamy, Jennifer Jean Meudt, Yongjun Liu, Laura M Lee, Kyle M Schachtschneider, Lawrence B Schook, Ron C Gaba, Lu Mao, Adnan Said and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Assessment of liver fibrosis and tumor burden in hepatocellular carcinoma using [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. [Scientific reports · 2026
    Article
  3. Review
  4. Radiology case reports · 2026
    Article
  5. A pilot human-based study ofScientific reports · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Efficacy of [Annals of nuclear medicine · 2025
    Article
  11. Cerebral [Translational stroke research · 2025
    Article
  12. Review
  13. Assessment of viable tumours by [European journal of nuclear medicine and molecular imaging · 2025
    Article
  14. Review
  15. Non-invasive visualization of liver fibrosis with [European journal of nuclear medicine and molecular imaging · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Ali PirastehRadiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin; pirasteh@wisc.edu.
Sarvesh PeriyasamyRadiology and Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Jennifer Jean MeudtAnimal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin.
Yongjun LiuPathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Laura M LeeResearch Animal Resources and Compliance, University of Wisconsin-Madison, Madison, Wisconsin.
Kyle M SchachtschneiderRadiology and Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois.
Lawrence B SchookAnimal Sciences, University of Illinois at Chicago, Chicago, Illinois.
Ron C GabaRadiology/Interventional Radiology, University of Illinois at Chicago, Chicago, Illinois.
Lu MaoBiostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.
Adnan SaidMedicine, Gastroenterology, and Hepatology, University of Wisconsin-Madison, Madison, Wisconsin.
Alan Blair McMillanRadiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Paul F LaesekeRadiology and Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Dhanansayan ShanmuganayagamAnimal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin.
University of Wisconsin–Madison · USUniversity of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

Integrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5M
Development of a Quantitative Angiography Technique for Characterizing Hepatic Perfusion Changes in Response to EmbolizationF30CA250408 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI PERIYASAMY, SARVESH · 2020 to 2022
$111k
NCI NIH HHS F30 CA250408NIGMS NIH HHS T32 GM140935
6 · The paper itself

Abstract

Current methods of staging liver fibrosis have notable limitations. We investigated the utility of PET in staging liver fibrosis by correlating liver uptake of

Indexed as

Gallium RadioisotopesLiver CirrhosisAnimalsFibroblastsMagnetic Resonance ImagingPositron-Emission TomographyPositron Emission Tomography Computed TomographySwineGallium Radioisotopesfibroblast activation protein inhibitorliver fibrosisMRIPETswine

Identifiers

PMID35450958
PMCPMC9730920
OpenAlexW4224256230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.