Evidence map›Paper›PMID 35450913›Full record

Trial reportBMJ open2022

Building knowledge, optimising physical and mental health and setting up healthier life trajectories in South African women (

Shane A Norris, Catherine E Draper, Alessandra Prioreschi, C M Smuts, Lisa Jayne Ware, CindyLee Dennis, Philip Awadalla, D Bassani, Zulfiqar Bhutta, Laurent Briollais and 26 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 55 citations in OpenAlex.

  1. Psychometric evaluation of the Pittsburgh Sleep Quality Index among South African women participating in the Bukhali trial: Healthy Life Trajectories Initiative.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Trial
  2. Retention in theBMJ global health · 2025
    Trial
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  5. Evaluating implementation of the FIGO Nutrition Checklist for preconception and pregnancy within the Bukhali trial in Soweto, South Africa.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Trial
  6. Article
  7. Early insights from the Healthy Life Trajectories Initiative.Bulletin of the World Health Organization · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 15 institutions in 4 countries.

Shane A NorrisSAMRC Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg-Braamfontein, South Africa shane.norris@wits.ac.za.ORCID 0000-0001-7124-3788
Catherine E DraperSAMRC Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.
Alessandra PrioreschiSAMRC Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.
C M SmutsCentre of Excellence of Nutrition, North-West University, Potchefstroom, South Africa.
Lisa Jayne WareSAMRC Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.ORCID 0000-0002-9762-4017
CindyLee DennisLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronton, Ontario, Canada.ORCID 0000-0002-0135-7242
Philip AwadallaDepartment of Molecular Genetics, Ontario Institute for Cancer Research, University of Toronto, Toronto, Ontario, Canada.
D BassaniCentre for Global Child Health, SickKids Research Institute, Toronto, Ontario, Canada.
Zulfiqar BhuttaCentre for Global Child Health, SickKids Research Institute, Toronto, Ontario, Canada.ORCID 0000-0003-0637-599X
Laurent BriollaisLunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
D William CameronMedicine, Division of Infectious Diseases, Ottawa Hospital General Campus, Ottawa, Ontario, Canada.
Tobias ChirwaSchool of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
B FallonFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
C M GrayDivision of Molecular Biology and Human Genetics, University of Stellenbosch, Stellenbosch, South Africa.
Jill HamiltonDepartment of Paediatrics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1958-2800
J JamisonCommunity Services, Red River College, Winnipeg, Manitoba, Canada.
Heather JaspanDivision of Immunology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, South Africa.
Jennifer JenkinsDepartment of Applied Psychology and Human Development, University of Toronto, Toronto, Ontario, Canada.
Kathleen KahnSchool of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
A P KengneNon-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Estelle V LambertDivision of Exercise Science and Sports Medicine, University of Cape Town, Rondebosch, South Africa.
Naomi LevittChronic Diseases Initiative for Africa, University of Cape Town, Cape Town, South Africa.
Marie-Claude MartinLunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
Michele RamsaySydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.
Daniel RothDepartment of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
Stephen SchererThe Hospital for Sick Children, Toronto, Ontario, Canada.
Daniel SellenDepartment of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
Wiedaad SlemmingDepartment of Paediatrics, University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.ORCID 0000-0002-1566-8228
Deborah SlobodaDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
M SzyfDepartment of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.
Stephen TollmanSchool of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
Mark TomlinsonInstitute for Life Course Health Research, University of Stellenbosch, Cape Town, South Africa.ORCID 0000-0001-5846-3444
Suzanne ToughDepartment of Paediatrics, Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.
Stephen G MatthewsLunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
Linda RichterDSI-NRF Centre of Excellence in Human Development, University of the Witwatersrand, Johannesburg, South Africa.
Stephen LyeSAMRC Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.
South African Medical Research Council · ZAUniversity of Toronto · CAUniversity of Cape Town · ZAUniversity of the Witwatersrand · ZALunenfeld-Tanenbaum Research Institute · CAAga Khan University · PKAlberta Children's Hospital · CACentre for Global Health Research · CAMcGill University · CAMcMaster University · CANorth-West University · ZAOntario Institute for Cancer Research · CAOttawa Hospital · CARed River College · CAStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSouth Africa's evolving burden of disease is challenging due to a persistent infectious disease, burgeoning obesity, most notably among women and rising rates of non-communicable diseases (NCDs). With two thirds of women presenting at their first antenatal visit either overweight or obese in urban South Africa (SA), the preconception period is an opportunity to optimise health and offset transgenerational risk of both obesity and NCDs. METHODS AND ANALYSIS: ETHICS AND DISSEMINATION: Ethical approval has been obtained from the Human Ethics Research Committee University of the Witwatersrand, Johannesburg, South Africa (M1811111), the University of Toronto, Canada (19-0066-E) and the WHO Ethics Committee (ERC.0003328). Data and biological sample sharing policies are consistent with the governance policy of the HeLTI Consortium (https://helti.org) and South African government legislation (POPIA). The recruitment and research team will obtain informed consent.

trial registrationThis trial is registered with the Pan African Clinical Trials Registry (https://pactr.samrc.ac.za) on 25 March 2019 (identifier: PACTR201903750173871). PROTOCOL VERSION: 20 March 2022 (version #4). Any protocol amendments will be communicated to investigators, Institutional Review Board (IRB)s, trial participants and trial registries.

Indexed as

Health StatusMental HealthChildChild, PreschoolCommunity Health WorkersFemaleHumansObesityPregnancySouth Africanutrition & dieteticspublic healthsocial medicine

Identifiers

PMID35450913
PMCPMC9024255
OpenAlexW4224238503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.