Evidence map›Paper›PMID 35450766›Full record

ReviewSeminars in cell & developmental biology2023

Mitochondrial respiratory quiescence: A new model for examining the role of mitochondrial metabolism in development.

Helin Hocaoglu, Matthew Sieber

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Redox regulation of meristem quiescence: outside/in.Journal of experimental botany · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Mitochondrial non-energetic function and embryonic cardiac development.Frontiers in cell and developmental biology · 2024
    Review
  12. Review
  13. Metabolic regulation of quiescence in plants.The Plant journal : for cell and molecular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Helin HocaogluDepartment of Physiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Matthew SieberDepartment of Physiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA. Electronic address: matthew.sieber@utsouthwestern.edu.
Southwestern Medical CenterSouthwestern Medical Center · US

Funding

Investigating the role of maternal metabolic reprogramming in progeny physiology and agingR01AG067604 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI SIEBER, MATTHEW · 2020 to 2024
$2.2M
NIA NIH HHS R01 AG067604
6 · The paper itself

Abstract

Mitochondria are vital organelles with a central role in all aspects of cellular metabolism. As a means to support the ever-changing demands of the cell, mitochondria produce energy, drive biosynthetic processes, maintain redox homeostasis, and function as a hub for cell signaling. While mitochondria have been widely studied for their role in disease and metabolic dysfunction, this organelle has a continually evolving role in the regulation of development, wound repair, and regeneration. Mitochondrial metabolism dynamically changes as tissues transition through distinct phases of development. These organelles support the energetic and biosynthetic demands of developing cells and function as key structures that coordinate the nutrient status of the organism with developmental progression. This review will examine the mechanisms that link mitochondria to developmental processes. We will also examine the process of mitochondrial respiratory quiescence (MRQ), a novel mechanism for regulating cellular metabolism through the biochemical and physiological remodeling of mitochondria. Lastly, we will examine MRQ as a system to discover the mechanisms that drive mitochondrial remodeling during development.

Indexed as

MitochondriaOrganellesEnergy MetabolismHomeostasisSignal TransductionCancerDrosophilaMetabolismMitochondriaOocytesQuiescenceReprogrammingStem cells

Identifiers

PMID35450766
PMCPMC9576824
OpenAlexW4224092504

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.