Evidence map›Paper›PMID 35450539›Full record

ArticleRecent advances in drug delivery and formulation2022

Recent Patents on Nasal Vaccines Containing Nanoadjuvants.

Francesco Candela, Eride Quarta, Francesca Buttini, Adolfo Ancona, Ruggero Bettini, Fabio Sonvico

Open access · hybridAbstract read
In one paragraph

Article in Recent advances in drug delivery and formulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Francesco CandelaDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Eride QuartaDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Francesca ButtiniDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Adolfo AnconaDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Ruggero BettiniDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Fabio SonvicoDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines are one of the greatest medical achievements of modern medicine. The nasal mucosa represents an effective route of vaccination for both mucosal immunity and peripheral, being at the same time an inductive and effector site of immunity. In this paper, the innovative and patented compositions and manufacturing procedures of nanomaterials have been studied using the peerreviewed research literature. Nanomaterials have several properties that make them unique as adjuvant for vaccines. Nanoadjuvants through the influence of antigen availability over time affect the immune response. Namely, the amount of antigen reaching the immune system or its release over prolonged periods of time can be effectively increased by nanoadjuvants. Mucosal vaccines are an interesting alternative for immunization of diseases in which pathogens access the body through these epithelia. Nanometric adjuvants are not only a viable approach to improve the efficacy of nasal vaccines but in most of the cases they represent the core of the intellectual property related to the innovative vaccine.

Indexed as

VaccinesAdjuvants, ImmunologicAntigensImmunity, MucosalImmunizationNasal MucosaAdjuvants, ImmunologicAntigensVaccinescellular immunityNanoadjuvantsnanoemulsionnanoparticlesnanotechnologynasal vaccine

Identifiers

PMID35450539
PMCPMC10184237
OpenAlexW4224214221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.