Evidence map›Paper›PMID 35450280›Full record

ReviewInterface focus2022

Principles, mechanisms and functions of entrainment in biological oscillators.

Alba Jiménez, Ying Lu, Ashwini Jambhekar, Galit Lahav

Abstract readReview
In one paragraph

Review in Interface focus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Rhythmic stimulation elicits multiple, concurrent neural responses.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Frontiers in cell and developmental biology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alba JiménezDepartment of Systems Biology, Blavatnik Institute at Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-9014-5857
Ying LuDepartment of Systems Biology, Blavatnik Institute at Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-3516-7735
Ashwini JambhekarDepartment of Systems Biology, Blavatnik Institute at Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-1078-6601
Galit LahavDepartment of Systems Biology, Blavatnik Institute at Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-4758-6427

Funding

Dynamics, Regulation and Function of p53 in Single CellsR35GM139572 · NIGMS · HARVARD MEDICAL SCHOOL · PI Galit Lahav · 2021 to 2026
$4.7M
Determine the mechanism of recognition of ubiquitin configurations by the 26S proteasomeR01GM134064 · NIGMS · HARVARD MEDICAL SCHOOL · PI LU, YING · 2019 to 2023
$1.9M
NIGMS NIH HHS R01 GM134064NIGMS NIH HHS R35 GM139572
6 · The paper itself

Abstract

Entrainment is a phenomenon in which two oscillators interact with each other, typically through physical or chemical means, to synchronize their oscillations. This phenomenon occurs in biology to coordinate processes from the molecular to organismal scale. Biological oscillators can be entrained within a single cell, between cells or to an external input. Using six illustrative examples of entrainable biological oscillators, we discuss the distinctions between entrainment and synchrony and explore features that contribute to a system's propensity to entrain. Entrainment can either enhance or reduce the heterogeneity of oscillations within a cell population, and we provide examples and mechanisms of each case. Finally, we discuss the known functions of entrainment and discuss potential functions from an evolutionary perspective.

Indexed as

Arnold tonguebiological oscillatorsentrainmentphase response curvesynchrony

Identifiers

PMID35450280
PMCPMC9010850

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.