Evidence map›Paper›PMID 35450217›Full record

ArticleFrontiers in genetics2022

The Association Between Cyclooxygenase-2 -1195G/A (rs689466) Gene Polymorphism and the Clinicopathology of Lung Cancer in the Japanese Population: A Case-Controlled Study.

Rong Sun, Ryosuke Tanino, Xuexia Tong, Minoru Isomura, Li-Jun Chen, Takamasa Hotta, Tamio Okimoto, Megumi Hamaguchi, Shunichi Hamaguchi, Yasuyuki Taooka and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Single-cell and spatial transcriptomics reveal an arachidonic acid-related cellular atlas in lung adenocarcinoma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  2. COX-2 in lung cancer: Mechanisms, development, and targeted therapies.Chronic diseases and translational medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Rong SunDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Ryosuke TaninoDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Xuexia TongDepartment of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, China.
Minoru IsomuraDepartment of Pathology, Shimane University Faculty of Medicine, Shimane University, Shimane, Japan.
Li-Jun ChenDepartment of Respiratory Medicine, Second Affiliated Hospital of Ningxia Medical University, Yinchuan, China.
Takamasa HottaDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Tamio OkimotoDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Megumi HamaguchiDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Shunichi HamaguchiDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Yasuyuki TaookaDivision of Internal Medicine, Department of Respiratory Medicine, Medical Corporation JR Hiroshima Hospital, Hiroshima, Japan.
Takeshi IsobeDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Yukari TsubataDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Faculty of Medicine, Shimane University, Shimane, Japan.
Shimane University · JPHiroshima General Hospital · JPNingxia Medical University · CNNingxia Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The single nucleotide polymorphisms of COX-2 gene, also known as

Indexed as

cyclooxygenase-2Japaneselung cancer riskpromoter regionsingle nucleotide polymorphismsquamous cell carcinoma

Identifiers

PMID35450217
PMCPMC9016323
OpenAlexW4225527454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.