Evidence map›Paper›PMID 35450177›Full record

ArticleInternational journal of ophthalmology2022

Clinical outcome of orbital apex syndrome in COVID associated mucormycosis patients in a tertiary care hospital.

Smiti Rani Srivastava, Purban Ganguly, Debasis Barman, Sudip Das, Manimoy Bandyopadhyay, Asim Kumar Ghosh, Subhra Sarkar, Amitabha Sengupta, Sarbari Swaika, Pritam Chatterjee and 8 more

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Visual perception alterations in COVID-19: a preliminary study.International journal of ophthalmology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Smiti Rani SrivastavaDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Purban GangulyDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Debasis BarmanDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Sudip DasDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Manimoy BandyopadhyayDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Asim Kumar GhoshDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Subhra SarkarDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Amitabha SenguptaDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Sarbari SwaikaDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Pritam ChatterjeeDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Amit Kumar GuptaDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Alok Ranjan MondalDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Soumyajit GuhaDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Sinjita DuttaDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Souvik AdhikariDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Aditi KaushikDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Partha Sundar BiswasDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Asif AyubDepartment of Ophthalmology; Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata 999008, India.
Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo share clinical pattern of presentation, the modalities of surgical intervention and the one month post-surgical outcome of rhino-orbito-mucormycosis (ROCM) cases.

methodsAll COVID associated mucormycosis (CAM) patients underwent comprehensive multidisciplinary examination by ophthalmologist, otorhinolaryngologist and physician. Patients with clinical and radiological evidence of orbital apex involvement were included in the study. Appropriate medical and surgical intervention were done to each patient. Patients were followed up one-month post intervention.

resultsOut of 89 CAM patients, 31 (34.8%) had orbital apex syndrome. Sixty-six (74.2%) of such patients had pre-existing diabetes mellitus, 18 (58%) patients had prior documented use of steroid use, and 55 (61.8%) had no light perception (LP) presenting vision. Blepharoptosis, proptosis, complete ophthalmoplegia were common clinical findings. Seventeen (19.1%) of such patients had variable amount of cavernous sinus involvement. Endoscopic debridement of paranasal sinuses and orbit with or without eyelid sparing limited orbital exenteration was done in most cases, 34 (38.2%) patients could retain vision in the affected eye.

conclusionOrbital apex involvement in CAM patients occur very fast. It not only leads to loss of vision but also sacrifice of the eyeball, orbital contents and eyelids. Early diagnosis and prompt intervention can preserve life, vision and spare mutilating surgeries.

Indexed as

COVID associated mucormycosisendoscopic paranasal sinus debridementorbital apex syndromeorbital exenterationrhino-orbito-cerebral mucormycosis

Identifiers

PMID35450177
PMCPMC8995734
OpenAlexW4220934745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.