Evidence map›Paper›PMID 35449993›Full record

ReviewJournal of medicine and life2022

A review and revisit of nanoparticles for antimicrobial drug delivery.

Kai Bin Liew, Ashok Kumar Janakiraman, Ramkanth Sundarapandian, Syed Haroon Khalid, Fizza Abdul Razzaq, Long Chiau Ming, Abdullah Khan, Anandarajagopal Kalusalingam, Pit Wei Ng

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of medicine and life, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Green Synthesis of Gold Nanoparticles UsingInternational journal of nanomedicine · 2025
    Article
  8. Article
  9. Article
  10. The good, the bad, and the ugly of metals as antimicrobials.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Kai Bin LiewDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Ashok Kumar JanakiramanDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Ramkanth SundarapandianDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Syed Haroon KhalidDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Fizza Abdul RazzaqDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Long Chiau MingDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Abdullah KhanDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Anandarajagopal KalusalingamDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
Pit Wei NgDepartment of Pharmaceutical Technology and Industry, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.
KPJ Healthcare UniversityNational University Hospital · SGUniversiti Brunei Darussalam · BNGovernment College University, Faisalabad · PKUCSI University · MYUniversity of Cyberjaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobials are widely used to treat bacteria, viruses, fungi, and protozoa. Therefore, research and development of newer types of antimicrobials are important. Antimicrobial resistance has emerged as a major challenge to the healthcare system, although various alternative antimicrobials have been proposed. However, none of these show consistent and comparable efficacy to antimicrobials in clinical trials. More recently, nanoparticles have emerged as a potential solution to antimicrobial agents to overcome antimicrobial resistance. This article revisits and updates applications of various types of nanoparticles for the delivery of antimicrobial agents and their characterization. Though nanoparticle technology has some limitations, it provides an innovative approach to pharmaceutical technology. Furthermore, nanoparticles offer a variety of advantages, such as enhancement of solubility and permeation, leading to better efficacy. In this article, approaches commonly employed to improve antimicrobial therapy are discussed. These approaches have advantages and applications and provide a broader opportunity for pharmaceutical scientists to choose the proper method per the desired outcome.

Indexed as

Anti-Infective AgentsNanoparticlesAnti-Bacterial AgentsBacteriaDrug Delivery SystemsHumansAnti-Bacterial AgentsAnti-Infective Agentsantibiotic, safetyanti-infective agentsnanomedicinenanoparticle

Identifiers

PMID35449993
PMCPMC9015166
OpenAlexW4224323741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.