Evidence map›Paper›PMID 35449863›Full record

ArticleJournal of healthcare engineering2022

Research on the Mechanism of HMGB1 Regulating Autoimmune Encephalomyelitis by Regulating NF-

Lijuan Liu, Jingtao Pang, Hui Yuan, Shengnu Qiu, Wei Zhang, Zhenzhu Shang, Xiaoting Liu

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lijuan LiuThe Third Department of Neurology, People's Hospital of Gaomi, Weifang, China.
Jingtao PangSecond Department of Encephalopathy, Weifang Hospital of Traditional Chinese Medicine, Weifang, China.
Hui YuanSecond Department of Encephalopathy, Weifang Hospital of Traditional Chinese Medicine, Weifang, China.
Shengnu QiuDivision of Biosciences, Faculty of Life Sciences, University College London, London, UK.
Wei ZhangSecond Department of Encephalopathy, Weifang Hospital of Traditional Chinese Medicine, Weifang, China.
Zhenzhu ShangSecond Department of Encephalopathy, Weifang Hospital of Traditional Chinese Medicine, Weifang, China.
Xiaoting LiuSecond Department of Encephalopathy, Weifang Hospital of Traditional Chinese Medicine, Weifang, China.ORCID 0000-0002-1884-4944
Weifang Chinese Medicine Hospital · CNUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autoimmune encephalomyelitis is a clinical condition in which memory and cognition is affected badly and is also associated with lower levels of consciousness or even coma in worse scenarios. It is a noninfectious condition which involves immune oriented inflammation. Objective: The study's goal was to figure out what was causing the problem HMGB1 involved in regulating the autoimmune encephalomyelitis by regulating NF- Materials and Methods: The expressions of HMGB1, miR-129-5p, and TLR4/NF- Results: According to the findings, miR-129-5p is in charge of suppressing HMGB1 production and inhibiting the TLR4/NF- Conclusion: According to the study's findings, there is indeed a link among increased miR-129-5p and decreased HMGB1 expression and also suppression of the TLR4/NF-

Indexed as

EncephalomyelitisHMGB1 ProteinMicroRNAsHumansInflammationNF-kappa BNF-kappa B p50 SubunitToll-Like Receptor 4HMGB1 ProteinHMGB1 protein, humanMicroRNAsMirn129 microRNA, humanNF-kappa BNF-kappa B p50 SubunitNFKB1 protein, humanToll-Like Receptor 4

Identifiers

PMID35449863
PMCPMC9017456
OpenAlexW4223492512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.