ArticleFrontiers in behavioral neuroscience2022
The Effect of Constraint-Induced Movement Therapy Combined With Repetitive Transcranial Magnetic Stimulation on Hand Function in Preschool Children With Unilateral Cerebral Palsy: A Randomized Controlled Preliminary Study.
Article in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Pooled it
- Noninvasive brain stimulation for upper limb motor activity in children and young adults with cerebral palsy and pediatric stroke: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2025Pooled it
- Effects of the combination of exercise with noninvasive brain stimulation on motor function and spasticity in children with cerebral palsy: A systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- Effects of theta burst stimulation on cognitive function and characteristics of blood oxygen alterations based on near-infrared spectroscopy in chronic schizophrenia.BMC psychiatry · 2025Trial
- Repetitive transcranial magnetic stimulation influences cognitive-motor dual-task performance in children with cerebral palsy: a randomized controlled study.Journal of neuroengineering and rehabilitation · 2025Trial
- Safety and feasibility of transcranial direct current stimulation stratified by corticospinal organization in children with hemiparesis.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2023Trial
- Restoring Functional Connectivity in Hemiplegic Cerebral Palsy: A Study of Low-Frequency rTMS Intervention.Journal of biomedical physics & engineering · 2025Article
- Non-invasive brain stimulation for upper extremity dysfunction in children with cerebral palsy: a systematic review and meta-analysis.Translational pediatrics · 2025Article
- Repetitive transcranial magnetic stimulation and constraint-induced movement therapy combined in the treatment of post-stroke movement disorders: a narrative review.Frontiers in human neuroscience · 2025Review
- Article
- Safety and effects of transcranial direct current stimulation on hand function in preschool children with hemiplegic cerebral palsy: A pilot study.Frontiers in behavioral neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Constraint-induced movement therapy (CIMT) combined with repetitive transcranial magnetic stimulation (rTMS) have shown great potential in improving function in schoolchildren with unilateral cerebral palsy attributed to perinatal stroke. However, the prospect of application in preschool children with unilateral cerebral palsy (UCP) attributed to various brain disorders remains unclear. In this prospective, assessor-blinded, randomized controlled study, 40 preschool children with UCP (aged 2.5-6 years) were randomized to receive 10 days of CIMT combined with active or sham rTMS. Assessments were performed at baseline, 2 weeks, and 6 months post-intervention to investigate upper limb extremity, social life ability, and perceived changes by parents and motor-evoked potentials. Overall, 35 participants completed the trial. The CIMT plus active stimulation group had greater gains in the affected hand function (range of motion, accuracy, and fluency) than the CIMT plus sham stimulation group (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.