Evidence map›Paper›PMID 35449448›Full record

ArticleJournal of exposure science & environmental epidemiology2023

Investigating geographic differences in environmental chemical exposures in maternal and cord sera using non-targeted screening and silicone wristbands in California.

Dana E Goin, Dimitri Abrahamsson, Miaomiao Wang, June-Soo Park, Marina Sirota, Rachel Morello-Frosch, Erin DeMicco, Jessica Trowbridge, Laura August, Steven O'Connell and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Dana E GoinProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Dimitri AbrahamssonProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Miaomiao WangEnvironmental Chemistry Laboratory, Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley, CA, USA.
June-Soo ParkProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Marina SirotaBakar Computational Health Sciences Institute and Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Rachel Morello-FroschDepartment of Environmental Science, Policy and Management and School of Public Health, University of California Berkeley, Berkeley, CA, USA.
Erin DeMiccoProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Jessica TrowbridgeProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Laura AugustOffice of Environmental Health Hazard Assessment, California Environmental Protection Agency, Sacramento, CA, USA.
Steven O'ConnellMyExposome, Inc., Corvallis, OR, USA.
Subhashini LadellaFresno Medical Education Program, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, Fresno, CA, USA.
Marya G ZlatnikProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Tracey J WoodruffProgram on Reproductive Health and the Environment, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA. tracey.woodruff@ucsf.edu.
University of California, San Francisco · USCalifornia Environmental Protection Agency · USCalifornia State University, Fresno · USUniversity of California, Berkeley · US

Funding

The Illinois Kids Development Study ECHO Pregnancy and Pediatric CohortUH3OD023272 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Andrea Aguiar, Susan L Schantz · 2018 to 2026
$18.6M
UCSF Environmental Research and Translation for Health Center (EaRTH Center)P30ES030284 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JENNIFER C FUNG, Tracey J. Woodruff · 2020 to 2026
$11.2M
The Illinois Kids Development Study ECHO Pregnancy and Pediatric CohortUG3OD023272 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SCHANTZ, SUSAN L · 2016 to 2024
$7.2M
Transdisciplinary Approach to Rapidly Identify Reproductive Toxics in Pregnant Women and NewbornsR01ES027051 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Dimitri Abrahamsson, Tracey J. Woodruff · 2016 to 2026
$6.6M
The UCSF Pregnancy Exposures to Environmental Chemicals (PEEC) Children's CenterP01ES022841 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, TRACEY J. · 2013 to 2018
$3.9M
NIEHS NIH HHS P01 ES022841NIEHS NIH HHS P30 ES030284NIEHS NIH HHS R01 ES027051NIH HHS UG3 OD023272NIH HHS UH3 OD023272
6 · The paper itself

Abstract

backgroundDifferential risks for adverse pregnancy outcomes may be influenced by prenatal chemical exposures, but current exposure methods may not fully capture data to identify harms and differences.

methodsWe collected maternal and cord sera from pregnant people in Fresno and San Francisco, and screened for over 2420 chemicals using LC-QTOF/MS. We matched San Francisco participants to Fresno participants (N = 150) and compared detection frequencies. Twenty-six Fresno participants wore silicone wristbands evaluated for over 1500 chemicals using quantitative chemical analysis. We assessed whether living in tracts with higher levels of pollution according to CalEnviroScreen correlated with higher numbers of chemicals detected in sera.

resultsWe detected 2167 suspect chemical features across maternal and cord sera. The number of suspect chemical features was not different by city, but a higher number of suspect chemicals in cosmetics or fragrances was detected in the Fresno versus San Francisco participants' sera. We also found high levels of chemicals used in fragrances measured in the silicone wristbands. Fresno participants living in tracts with higher pesticide scores had higher numbers of suspect pesticides in their sera.

conclusionsMultiple exposure-assessment approaches can identify exposure to many chemicals during pregnancy that have not been well-studied for health effects.

Indexed as

Environmental MonitoringPesticidesCaliforniaEnvironmental ExposureFemaleHumansPregnancySiliconesPesticidesSiliconesEnvironmental disparities, cord bloodExposure assessmentNon-targeted chemical analysisPesticide;PhthalatePregnancySilicone wristbands

Identifiers

PMID35449448
PMCPMC9585116
OpenAlexW4224267138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.