Evidence map›Paper›PMID 35449407›Full record

ReviewNature reviews. Cardiology2022

Optical coherence tomography in coronary atherosclerosis assessment and intervention.

Makoto Araki, Seung-Jung Park, Harold L Dauerman, Shiro Uemura, Jung-Sun Kim, Carlo Di Mario, Thomas W Johnson, Giulio Guagliumi, Adnan Kastrati, Michael Joner and 104 more

Erratum issuedOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 207 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
207citing papers in PubMed, 5 pooled it
74.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

207 citing papers in PubMed, 5 syntheses or guidelines pooled it, 368 citations in OpenAlex.

  1. Pooled it
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  6. Trial
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  9. Preclinical Serial Assessment of Virtual Physiology After Implantation of a Novel Endoluminal Resorbable Fibrillated Scaffold.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  10. Article
  11. Molecular phenotyping withEuropean journal of nuclear medicine and molecular imaging · 2026
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  12. Review
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  17. Review
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  19. Is Imaging of a Single Vessel Sufficient to Assess Pan-Coronary Vulnerability?Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  20. Article

147 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

114 authors at 20 institutions in 20 countries.

Makoto ArakiMassachusetts General Hospital, Boston, MA, USA.
Seung-Jung ParkAsan Medical Center, Seoul, South Korea.
Harold L DauermanUniversity of Vermont, Burlington, VT, USA.
Shiro UemuraKawasaki Medical School, Okayama, Japan.
Jung-Sun KimYonsei University College of Medicine, Seoul, South Korea.
Carlo Di MarioCareggi University Hospital, Florence, Italy.ORCID http://orcid.org/0000-0002-4461-2055
Thomas W JohnsonUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Giulio GuagliumiOspedale Papa Giovanni XXIII, Bergamo, Italy.
Adnan KastratiTechnische Universität München and Munich Heart Alliance, Munich, Germany.
Michael JonerGerman Heart Center, Munich, Germany.
Niels Ramsing HolmAarhus University Hospital, Skejby, Denmark.
Fernando AlfonsoHospital Universitario La Princesa, Madrid, Spain.
William WijnsNational University of Ireland Galway and Saolta University Healthcare Group, Galway, Ireland.ORCID http://orcid.org/0000-0002-7267-4376
Tom AdriaenssensUniversity Hospitals Leuven, Leuven, Belgium.
Holger NefUniversity of Giessen, Giessen, Germany.
Gilles RioufolHospices Civils de Lyon and Claude Bernard University, Lyon, France.
Nicolas AmabileInstitut Mutualiste Montsouris, Paris, France.
Geraud SouteyrandUniversity Hospital of Clermont Ferrand, Clermont-Ferrand, France.
Nicolas MeneveauUniversity Hospital Jean Minjoz, Besançon, France.
Edouard GerbaudUniversity Hospital of Bordeaux, Pessac, France.ORCID http://orcid.org/0000-0003-4669-3562
Maksymilian P OpolskiNational Institute of Cardiology, Warsaw, Poland.
Nieves GonzaloHospital Clinico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Guillermo J TearneyMassachusetts General Hospital, Boston, MA, USA.
Brett BoumaMassachusetts General Hospital, Boston, MA, USA.
Aaron D AguirreMassachusetts General Hospital, Boston, MA, USA.
Gary S MintzCardiovascular Research Foundation, New York, NY, USA.
Gregg W StoneIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Christos V BourantasBarts Health NHS Trust, University College London and Queen Mary University London, London, UK.
Lorenz RäberInselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Sebastiano GiliCentro Cardiologico Monzino, IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0002-0542-0448
Kyoichi MizunoMitsukoshi Health and Welfare Foundation, Tokyo, Japan.
Shigeki KimuraYokohama Minami Kyosai Hospital, Kanagawa, Japan.
Toshiro ShinkeShowa University Hospital, Tokyo, Japan.
Myeong-Ki HongYonsei University College of Medicine, Seoul, South Korea.
Yangsoo JangYonsei University College of Medicine, Seoul, South Korea.ORCID http://orcid.org/0000-0002-2169-3112
Jin Man ChoKyung Hee University, Seoul, South Korea.
Bryan P YanChinese University of Hong Kong, Hong Kong, Hong Kong.
Italo PortoUniversity of Genoa, Genoa, Italy, San Martino Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy.ORCID http://orcid.org/0000-0002-9854-5046
Giampaolo NiccoliUniversity of Parma, Parma University Hospital, Parma, Italy.
Rocco A MontoneFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID http://orcid.org/0000-0002-6439-1018
Vikas ThondapuMassachusetts General Hospital, Boston, MA, USA.
Michail I PapafaklisUniversity Hospital of Ioannina, Ioannina, Greece.ORCID http://orcid.org/0000-0002-5646-0378
Lampros K MichalisUniversity Hospital of Ioannina, Ioannina, Greece.
Harmony ReynoldsNew York University Grossman School of Medicine, New York, NY, USA.
Jacqueline SawVancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Peter LibbyBrigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1502-502X
Giora WeiszNew York Presbyterian Hospital, Columbia University Medical Center and Cardiovascular Research Foundation, New York, NY, USA.
Mario IannacconeOspedale San Giovanni Bosco, Turin, Italy.ORCID http://orcid.org/0000-0003-0571-3918
Tommaso GoriUniversitäts medizin Mainz and DZHK Rhein-Main, Mainz, Germany.
Konstantinos ToutouzasNational and Kapodistrian University of Athens, Athens, Greece.
Taishi YonetsuTokyo Medical and Dental University, Tokyo, Japan.
Yoshiyasu MinamiKitasato University School of Medicine, Kanagawa, Japan.
Masamichi TakanoNippon Medical School Chiba Hokusoh Hospital, Chiba, Japan.
O Christopher RaffelThe Prince Charles Hospital, Chermside, Queensland, Australia.
Osamu KuriharaNippon Medical School Chiba Hokusoh Hospital, Chiba, Japan.
Tsunenari SoedaNara Medical University, Nara, Japan.
Tomoyo SugiyamaTsuchiura Kyodo General Hospital, Ibaraki, Japan.
Hyung Oh KimKyung Hee University, Seoul, South Korea.
Tetsumin LeeJapanese Red Cross Musashino Hospital, Tokyo, Japan.
Takumi HigumaKawasaki Municipal Tama Hospital, St. Marianna University School of Medicine, Kanagawa, Japan.
Akihiro NakajimaMassachusetts General Hospital, Boston, MA, USA.
Erika YamamotoKyoto University Graduate School of Medicine, Kyoto, Japan.
Krzysztof L BryniarskiJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, Krakow, Poland.ORCID http://orcid.org/0000-0001-9251-7610
Luca Di VitoMazzoni Hospital, Ascoli Piceno, Italy.
Rocco VergalloCatholic University of the Sacred Heart, Rome, Italy.
Francesco FracassiCatholic University of the Sacred Heart, Rome, Italy.ORCID http://orcid.org/0000-0002-8099-1224
Michele RussoCatholic University of the Sacred Heart, Rome, Italy.
Lena M SeegersMassachusetts General Hospital, Boston, MA, USA.
Iris McNultyMassachusetts General Hospital, Boston, MA, USA.
Sangjoon ParkKorea Advanced Institute of Science and Technology, Daejeon, South Korea.
Marc FeldmanUniversity of Texas Health, San Antonio, TX, USA.
Javier EscanedHospital Clínico San Carlos, Madrid, Spain.ORCID http://orcid.org/0000-0003-4932-0112
Francesco PratiUniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy.
Eloisa ArbustiniIRCCS Foundation University Hospital Policlinico San Matteo, Pavia, Italy.
Fausto J PintoSanta Maria University Hospital, CHULN Center of Cardiology of the University of Lisbon, Lisbon School of Medicine, Lisbon Academic Medical Center, Lisbon, Portugal.ORCID http://orcid.org/0000-0002-8034-4529
Ron WaksmanMedStar Washington Hospital Center, Washington, DC, USA.
Hector M Garcia-GarciaMedStar Washington Hospital Center, Washington, DC, USA.ORCID http://orcid.org/0000-0001-5100-0471
Akiko MaeharaCardiovascular Research Foundation, New York, NY, USA.
Ziad AliCardiovascular Research Foundation, New York, NY, USA.
Aloke V FinnCV Path Institute, Gaithersburg, MD, USA.
Renu VirmaniCV Path Institute, Gaithersburg, MD, USA.
Annapoorna S KiniMount Sinai Hospital, New York, NY, USA.
Joost DaemenErasmus University Medical Centre, Rotterdam, Netherlands.
Teruyoshi KumeKawasaki Medical School, Okayama, Japan.ORCID http://orcid.org/0000-0002-7815-9789
Kiyoshi HibiYokohama City University Medical Center, Kanagawa, Japan.
Atsushi TanakaWakayama Medical University, Wakayama, Japan.
Takashi AkasakaWakayama Medical University, Wakayama, Japan.
Takashi KuboWakayama Medical University, Wakayama, Japan.
Satoshi YasudaTohoku University Graduate School of Medicine, Sendai, Japan.
Kevin CroceBrigham and Women's Hospital, Boston, MA, USA.
Juan F GranadaCardiovascular Research Foundation, New York, NY, USA.
Amir LermanMayo Clinic, Rochester, MN, USA.
Abhiram PrasadMayo Clinic, Rochester, MN, USA.
Evelyn RegarUniversity Hospital Zürich, Zürich, Switzerland.
Yoshihiko SaitoGifu University Graduate School of Medicine, Gifu, Japan.
Mullasari Ajit SankardasMadras Medical Mission, Chennai, India.ORCID http://orcid.org/0000-0003-2968-0057
Vijayakumar SubbanMadras Medical Mission, Chennai, India.
Neil J WeissmanMedStar Health Research Institute, Washington, DC, USA.
Yundai ChenSixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Bo YuThe Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Stephen J NichollsMonash University, Melbourne, Victoria, Australia.
Peter BarlisUniversity of Melbourne, Melbourne, Victoria, Australia.
Nick E J WestRoyal Papworth Hospital, Cambridge, UK.
Armin Arbab-ZadehJohns Hopkins University, Baltimore, MD, USA.
Jong Chul YeKorea Advanced Institute of Science and Technology, Daejeon, South Korea.
Jouke DijkstraLeiden University Medical Centre, Leiden, Netherlands.ORCID http://orcid.org/0000-0002-8666-3731
Hang LeeMassachusetts General Hospital, Boston, MA, USA.
Jagat NarulaIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Filippo CreaCatholic University of the Sacred Heart, Rome, Italy.
Sunao NakamuraNew Tokyo Hospital, Chiba, Japan.
Tsunekazu KakutaTsuchiura Kyodo General Hospital, Ibaraki, Japan.
James FujimotoMassachusetts Institute of Technology, Cambridge, MA, USA.
Valentin FusterIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Ik-Kyung JangMassachusetts General Hospital, Boston, MA, USA. ijang@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-5796-3006
Massachusetts General Hospital · USUniversità Cattolica del Sacro Cuore · ITCardiovascular Research Foundation · USIcahn School of Medicine at Mount Sinai · USKorea Advanced Institute of Science and Technology · KRKyung Hee University · KRWakayama Medical University · JPYonsei University · KRBrigham and Women's Hospital · USChiba Hokusou Hospital · JPCVPath Institute · USHospital Clínico San Carlos · ESKawasaki Medical School · JPMadras Medical Mission · INMayo Clinic in Arizona · USMedStar Washington Hospital Center · USTsuchiura Kyodo General Hospital · JPUniversity Hospital of Ioannina · GRAarhus University Hospital · DKAzienda Ospedaliero-Universitaria Careggi · IT

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Namati · 2012 to 2026
$22.4M
IL1beta signaling in SMCpromotes beneficial changes in late stage atherosclerotic lesion pathogenesisR01HL141425 · NHLBI · UNIVERSITY OF VIRGINIA · PI OWENS, GARY K · 2019 to 2022
$3.1M
NHLBI NIH HHS R01 HL141425NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in the management of patients with acute coronary syndromes. Detection by OCT of healed coronary plaque has been important in our understanding of the mechanisms involved in plaque destabilization and healing with the rapid progression of atherosclerosis. Accurate detection by OCT of sequelae from percutaneous coronary interventions that might be missed by angiography could improve clinical outcomes. In addition, OCT has become an essential diagnostic modality for myocardial infarction with non-obstructive coronary arteries. Insight into neoatherosclerosis from OCT could improve our understanding of the mechanisms of very late stent thrombosis. The appropriate use of OCT depends on accurate interpretation and understanding of the clinical significance of OCT findings. In this Review, we summarize the state of the art in cardiac OCT and facilitate the uniform use of this modality in coronary atherosclerosis. Contributions have been made by clinicians and investigators worldwide with extensive experience in OCT, with the aim that this document will serve as a standard reference for future research and clinical application.

Indexed as

AtherosclerosisCoronary Artery DiseaseMyocardial InfarctionPercutaneous Coronary InterventionPlaque, AtheroscleroticCoronary AngiographyCoronary VesselsHumansStentsTomography, Optical Coherence

Identifiers

PMID35449407
PMCPMC9982688
OpenAlexW4224230408

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.