Evidence map›Paper›PMID 35449343›Full record

Observational studyNeurocritical care2022

Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage: Relation to Neurointensive Care Targets.

Teodor Svedung Wettervik, Henrik Engquist, Anders Hånell, Timothy Howells, Elham Rostami, Elisabeth Ronne-Engström, Anders Lewén, Per Enblad

Erratum issuedAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Neurocritical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. High risk and low incidence diseases: Aneurysmal subarachnoid hemorrhage.The American journal of emergency medicine · 2025
    Review
  4. Observational
  5. Article
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  8. Review
  9. Article
  10. Observational
  11. Review
  12. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Teodor Svedung WettervikSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden. teodor.svedung-wettervik@neuro.uu.se.ORCID http://orcid.org/0000-0002-4556-5721
Henrik EngquistDepartment of Surgical Sciences/Anesthesia and Intensive Care, Uppsala University, Uppsala, Sweden.
Anders HånellSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Timothy HowellsSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Elham RostamiSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Elisabeth Ronne-EngströmSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Anders LewénSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Per EnbladSection of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary aim was to determine to what extent continuously monitored neurointensive care unit (neuro-ICU) targets predict cerebral blood flow (CBF) and delivery of oxygen (CDO

methodsIn this observational study, patients with aneurysmal subarachnoid hemorrhage treated at the neuro-ICU in Uppsala, Sweden, from 2012 to 2020 with at least one xenon-enhanced computed tomography (Xe-CT) obtained within the first 14 days post ictus were included. CBF was measured with the Xe-CT and CDO

resultsOf 148 patients, 27 had underwent a Xe-CT only in the early phase, 74 only in the vasospasm phase, and 47 patients in both phases. The patients exhibited cerebral hypoperfusion and poor CDO

conclusionsSystemic and cerebral physiological variables exhibited a modest association with CBF and CDO

Indexed as

Subarachnoid HemorrhageCerebrovascular CirculationHumansIntracranial PressureOxygenXenonOxygenXenonAneurysmal subarachnoid hemorrhageCerebral blood flowCerebral oxygen delivery (cerebral pressure autoregulation)Clinical outcomeXenon-enhanced computed tomography

Identifiers

PMID35449343
PMCPMC9283361

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.