Evidence map›Paper›PMID 35449018›Full record

ArticleBMC health services research2022

Clinical variation in the organization of clinical pathways in esophagogastric cancer, a mixed method multiple case study.

J C H B M Luijten, P A J Vissers, L Brom, M de Bièvre, J Buijsen, T Rozema, N Haj Mohammad, P van Duijvendijk, E A Kouwenhoven, W J Eshuis and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

J C H B M LuijtenDepartment of Research & Development, Netherlands Comprehensive Cancer Organization (IKNL), Godebaldkwartier 419, 3511, DT, Utrecht, The Netherlands. j.luijten@iknl.nl.
P A J Vissers *Department of Research & Development, Netherlands Comprehensive Cancer Organization (IKNL), Godebaldkwartier 419, 3511, DT, Utrecht, The Netherlands.
L BromDepartment of Research & Development, Netherlands Comprehensive Cancer Organization (IKNL), Godebaldkwartier 419, 3511, DT, Utrecht, The Netherlands.
M de BièvreDepartment of Gastroenterology, Viecuri Medical Center, Venlo, The Netherlands.
J BuijsenDepartment of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
T RozemaDepartment of Radiation Oncology, Verbeten Insitute, Tilburg, The Netherlands.
N Haj MohammadDepartment of Medical Oncology, Utrecht UMC, Utrecht University, Utrecht, The Netherlands.
P van DuijvendijkDepartment of Surgery, Gelre Hospital, Apeldoorn, The Netherlands.
E A KouwenhovenDepartment of Surgery, ZGT, Almelo, The Netherlands.
W J EshuisDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
C RosmanDepartment of Surgery, Radboudumc, Nijmegen, The Netherlands.
P D SiersemaDepartment of Gastroenterology, Radboudumc, Nijmegen, The Netherlands.
H W M van LaarhovenDepartment of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
R H A Verhoeven *Department of Research & Development, Netherlands Comprehensive Cancer Organization (IKNL), Godebaldkwartier 419, 3511, DT, Utrecht, The Netherlands. r.verhoeven@iknl.n.
G A P Nieuwenhuijzen *Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands.
M J Westerman *Department of Epidemiology and Datascience, Amsterdam UMC, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLRadboud University Nijmegen · NLNetherlands Comprehensive Cancer Organisation · NLGelre Hospitals · NLInstituut Verbeeten · NLMaastro Clinic · NLRadboud University Medical Center · NLUtrecht University · NLVieCuri Medisch Centrum · NLZiekenhuis Groep Twente · NL

Funding

KWF Kankerbestrijding Project No. 10895
6 · The paper itself

Abstract

backgroundAmong esophagogastric cancer patients, the probability of having undergone treatment with curative intent has been shown to vary, depending on the hospital of diagnosis. However, little is known about the factors that contribute to this variation. In this study, we sought to understand the organization of clinical pathways and their association with variation in practice.

methodsA mixed-method study using quantitative and qualitative data was conducted. Quantitative data were obtained from the Netherlands Cancer Registry (e.g., outpatient clinic consultations and diagnostic procedures). For qualitative data, thematic content analysis was performed using semi-structured interviews (n = 30), observations of outpatient clinic consultations (n = 26), and multidisciplinary team meetings (MDTM, n = 16) in eight hospitals, to assess clinicians' perspectives regarding the clinical pathways.

resultsQuantitative analyses showed that patients more often underwent surgical consultation prior to the MDTM in hospitals associated with a high probability of receiving treatment with curative intent, but more often consulted with a geriatrician in hospitals associated with a low probability of such treatment. The organization of clinical pathways was analyzed quantitatively at three levels: regional, local, and patient levels. At a regional level, hospitals differed in terms of the number of patients discussed during the MDTM. At the local level, the revision of radiological images and restaging after neoadjuvant treatment varied. At the patient level, some hospitals routinely conduct fitness tests, whereas others estimated the patient's physical fitness during an outpatient clinic consultation. Few clinicians performed a standard geriatric consultation in older patients to assess their mental fitness and frailty.

conclusionSurgical consultation prior to MDTM was more often conducted in hospitals associated with a high probability of receiving treatment with curative intent, whereas a geriatrician was consulted more often in hospitals associated with a low probability of receiving such treatment.

Indexed as

Esophageal NeoplasmsStomach NeoplasmsAgedCritical PathwaysHospitalsHumansProbabilityCancer medicineEsophageal cancerGastric cancerVariation in clinical pathways

Identifiers

PMID35449018
PMCPMC9022421
OpenAlexW4224232696

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.