ReviewToxins2022
Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern.
Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07313371 (Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder), which is not on this map. Cited by 66 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder: a Randomized Clinical Trial.
Who cites it
66 citing papers in PubMed, 3 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Children's exposure to cocaine detected by hair analysis: a systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- miRNAs and Substances Abuse: Clinical and Forensic Pathological Implications: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Subcellular Effectors of Cocaine Cardiotoxicity: All Roads Lead to Mitochondria-A Systematic Review of the Literature.International journal of molecular sciences · 2023Pooled it
- Fatty Acid-Binding Proteins and Substance Use Disorders: From Lipid Signaling to Therapeutic Targets.Genes · 2026Review
- Cocaine-Induced Ocular Toxicity.Diseases (Basel, Switzerland) · 2026Review
- Review
- Transformation-Aware Molecular Networking for Interpretation of Untargeted LC-HRMS Data.ACS measurement science au · 2026Article
- Cocaine-Induced Plasma Cell Dermatomucositis (CI-PCDM): Clinical and Histopathological Features of a UK Cohort.Head and neck pathology · 2026Article
- Psychopharmacology of Methamphetamine in Relation to the United Kingdom Sentencing Guidance: Comparative Analysis with Amphetamine, Cocaine and Heroin.Brain sciences · 2026Article
- Non-Psychoactive Cannabis Extract Disrupts Reinstatement and Reconsolidation in Cocaine-Induced Conditioned Place Preference in Mice.Brain sciences · 2026Article
- Cocaine Use Disorder: Neuropathology and Exploratory Treatments.Molecular neurobiology · 2026Review
- From Neuroadaptation to Neuroprogression: Rethinking Chronic Cocaine Exposure Through a Model of Cocaine-Related Cerebropathy.Journal of clinical medicine · 2026Article
- Disruption of Dopamine Homeostasis by Psychostimulants.Molecular neurobiology · 2026Review
- Review
- Addictive drug abuse and depression-a focus on epigenetics.Communications biology · 2026Review
- Pharmacological topics of interest for young people: misinformation on TikTok is common.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Invisible victims: rising pediatric cocaine exposures in France (2020-2024) - insights from the national poison center database.Frontiers in toxicology · 2026Article
- Article
- Gastrointestinal complications of cocaine use: a narrative literature review.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026Review
- The Diagnosis and Treatment of Stimulant-Related Emergencies.Deutsches Arzteblatt international · 2025Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cocaine is one of the most consumed stimulants throughout the world, as official sources report. It is a naturally occurring sympathomimetic tropane alkaloid derived from the leaves of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.