Evidence map›Paper›PMID 35448876›Full record

ArticleToxins2022

Lipopolysaccharide from the Cyanobacterium

Julie A Swartzendruber, Rosalinda Monroy Del Toro, Ryan Incrocci, Nessa Seangmany, Joshua R Gurr, Alejandro M S Mayer, Philip G Williams, Michelle Swanson-Mungerson

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Cytotoxic and Immunomodulatory Effects ofInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Julie A SwartzendruberDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA.ORCID 0000-0002-1598-9267
Rosalinda Monroy Del ToroDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA.
Ryan IncrocciDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA.
Nessa SeangmanyBiomedical Sciences Program, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA.
Joshua R GurrDepartment of Chemistry, University of Hawaii-Manoa, Honolulu, HI 96822, USA.
Alejandro M S MayerDepartment of Pharmacology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA.ORCID 0000-0002-8358-4528
Philip G WilliamsDepartment of Chemistry, University of Hawaii-Manoa, Honolulu, HI 96822, USA.ORCID 0000-0001-8987-0683
Michelle Swanson-MungersonDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA.ORCID 0000-0001-6384-6933
Midwestern University · USUniversity of Hawaiʻi at Mānoa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucocorticoid-resistant asthma, which predominates with neutrophils instead of eosinophils, is an increasing health concern. One potential source for the induction of neutrophil-predominant asthma is aerosolized lipopolysaccharide (LPS). Cyanobacteria have recently caused significant tidal blooms, and aerosolized cyanobacterial LPS has been detected near the cyanobacterial overgrowth. We hypothesized that cyanobacterial LPS contributes to lung inflammation by increasing factors that promote lung inflammation and neutrophil recruitment. To test this hypothesis, c57Bl/6 mice were exposed intranasally to LPS from the cyanobacterium member,

Indexed as

AsthmaCyanobacteriaPneumoniaAnimalsChemokinesCytokinesGlucocorticoidsInflammationIntercellular Adhesion Molecule-1LipopolysaccharidesLungMiceNeutrophil InfiltrationNeutrophilsChemokinesCytokinesGlucocorticoidsIntercellular Adhesion Molecule-1Lipopolysaccharidescyanobacteriaglucocorticoid-resistant asthmalipopolysaccharidelung inflammationneutrophils

Identifiers

PMID35448876
PMCPMC9024439
OpenAlexW4223471939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.