Evidence map›Paper›PMID 35448592›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Integration of In Silico and In Vitro Analysis of Gliotoxin Production Reveals a Narrow Range of Producing Fungal Species.

Sergio Redrado, Patricia Esteban, María Pilar Domingo, Concepción Lopez, Antonio Rezusta, Ariel Ramirez-Labrada, Maykel Arias, Julián Pardo, Eva M Galvez

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Sergio RedradoInstituto de Carboquımica ICB-CSIC, 50018 Zaragoza, Spain.ORCID 0000-0002-8404-0012
Patricia EstebanBiomedical Research Centre of Aragon (CIBA), Fundacion Instituto de Investigacion Sanitaria Aragon (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0003-4123-3524
María Pilar DomingoInstituto de Carboquımica ICB-CSIC, 50018 Zaragoza, Spain.ORCID 0000-0002-6829-8769
Concepción LopezDepartment of Microbiology, Hospital Universitario Miguel Servet, IIS Aragón, 50009 Zaragoza, Spain.ORCID 0000-0001-6840-3138
Antonio RezustaDepartment of Microbiology, Hospital Universitario Miguel Servet, IIS Aragón, 50009 Zaragoza, Spain.
Ariel Ramirez-LabradaBiomedical Research Centre of Aragon (CIBA), Fundacion Instituto de Investigacion Sanitaria Aragon (IIS Aragon), 50009 Zaragoza, Spain.
Maykel AriasBiomedical Research Centre of Aragon (CIBA), Fundacion Instituto de Investigacion Sanitaria Aragon (IIS Aragon), 50009 Zaragoza, Spain.
Julián PardoBiomedical Research Centre of Aragon (CIBA), Fundacion Instituto de Investigacion Sanitaria Aragon (IIS Aragon), 50009 Zaragoza, Spain.
Eva M GalvezInstituto de Carboquımica ICB-CSIC, 50018 Zaragoza, Spain.ORCID 0000-0001-6928-5516
Instituto de Carboquímica · ESInstituto de Investigación Sanitaria Aragón · ESHospital Universitario Miguel Servet · ESUniversidad de Zaragoza · ES

Funding

Aspanoa AspanoaDGA predoctoral contract S.R.FEDER (Fondo Europeo de Desarrollo Regional), Gobierno de Aragon Group B29_20RFondo Garantıa Empleo Juvenil/INAEM P.E.Fundacion Aragon I+D (ARAID) J.P.GILEAD GLD18/00100Juan de la Cierva contract of Spanish Ministry of Economy and Competitiveness IJC2019-039192-IMinisterio de Ciencia, Innovación e Universidades (MCNU), Agencia Estatal de Investigación (SAF2017-83120-C2-1-R; PID2020-113963RB-I00)
6 · The paper itself

Abstract

Gliotoxin is a fungal secondary metabolite with impact on health and agriculture since it might act as virulence factor and contaminate human and animal food. Homologous gliotoxin (GT) gene clusters are spread across a number of fungal species although if they produce GT or other related epipolythiodioxopiperazines (ETPs) remains obscure. Using bioinformatic tools, we have identified homologous gli gene clusters similar to the

Indexed as

bisdethiobis(methylthio)gliotoxinepipolythiodioxopiperazinesgli clustergliotoxinNRPS

Identifiers

PMID35448592
PMCPMC9030297
OpenAlexW4220874425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.