Evidence map›Paper›PMID 35448553›Full record

ArticleMetabolites2022

iNovo479: Metabolic Modeling Provides a Roadmap to Optimize Bioproduct Yield from Deconstructed Lignin Aromatics by

Alexandra M Linz, Yanjun Ma, Samuel Scholz, Daniel R Noguera, Timothy J Donohue

Abstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Obtaining PDC and other high-added value products from lignin byJournal of integrative bioinformatics · 2025
    Article
  3. Tools for genetic engineering and gene expression control inApplied and environmental microbiology · 2024
    Article
  4. Article
  5. Article
  6. Tools for Genetic Engineering and Gene Expression Control inbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandra M LinzDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.ORCID 0000-0002-7551-4810
Yanjun MaDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
Samuel ScholzDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.ORCID 0000-0001-9716-0606
Daniel R NogueraDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.ORCID 0000-0003-0372-3063
Timothy J DonohueDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.ORCID 0000-0001-8738-2467

Funding

Great Lakes Bioenergy Research Center DE-SC0018409
6 · The paper itself

Abstract

Lignin is an abundant renewable source of aromatics and precursors for the production of other organic chemicals. However, lignin is a heterogeneous polymer, so the mixture of aromatics released during its depolymerization can make its conversion to chemicals challenging. Microbes are a potential solution to this challenge, as some can catabolize multiple aromatic substrates into one product.

Indexed as

aromatic metabolismlignin conversionmetabolic modelingthermodynamics

Identifiers

PMID35448553
PMCPMC9028409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.