Evidence map›Paper›PMID 35448552›Full record

ArticleMetabolites2022

Early Effects of Metabolic Syndrome on ATP-Sensitive Potassium Channels from Rat Pancreatic Beta Cells.

Iskra Cruz-Cruz, Germán Bernate-Obando, Carlos Larqué, Rene Escalona, Rodolfo Pinto-Almazán, Myrian Velasco

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Iskra Cruz-CruzNeuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, AP 70-253 Coyoacán, México City 04510, Mexico.
Germán Bernate-ObandoNeuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, AP 70-253 Coyoacán, México City 04510, Mexico.ORCID 0000-0003-4625-2329
Carlos LarquéEmbriology and Genetics Deparment, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, AP 70-253 Coyoacán, México City 04510, Mexico.ORCID 0000-0003-0634-195X
Rene EscalonaEmbriology and Genetics Deparment, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, AP 70-253 Coyoacán, México City 04510, Mexico.ORCID 0000-0001-6559-6712
Rodolfo Pinto-AlmazánNon-Communicable Disease Research Group, Facultad Mexicana de Medicina, Universidad La Salle-México, Las Fuentes 17, Tlalpan Centro I, Tlalpan, México City 14000, Mexico.ORCID 0000-0002-5210-5395
Myrian VelascoNeuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, AP 70-253 Coyoacán, México City 04510, Mexico.ORCID 0000-0002-9276-1928
Universidad Nacional Autónoma de México · MXUniversidad La Salle · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome (MS) is a cluster of metabolic signs that increases the risk of developing type 2 two diabetes mellitus and cardiovascular diseases. MS leads to pancreatic beta cell exhaustion and decreased insulin secretion through unknown mechanisms in a time-dependent manner. ATP-sensitive potassium channels (K

Indexed as

glybenclamideinsulinKATP channelsmetabolic syndromepancreatic beta cell

Identifiers

PMID35448552
PMCPMC9030496
OpenAlexW4224291266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.