Evidence map›Paper›PMID 35448516›Full record

ArticleMetabolites2022

Low-Concentrations of Fatty Acids Induce an Early Increase in IL-8 Levels in Normal Human Astrocytes.

Ana-Maria Dobri, Elena Codrici, Ionela-Daniela Popescu, Lucian Albulescu, Emanuel Tudor Fertig, Ana-Maria Enciu, Cristiana Tanase, Mihail E Hinescu

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ana-Maria Dobri"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
Elena Codrici"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
Ionela-Daniela Popescu"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
Lucian Albulescu"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
Emanuel Tudor Fertig"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
Ana-Maria Enciu"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-8122-1096
Cristiana Tanase"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
Mihail E Hinescu"Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-7740-9336
Carol Davila University of Medicine and Pharmacy · ROInstitutul National Victor Babes · ROTitu Maiorescu University · RO

Funding

Ministry of Education and Research in Romania 31PFE/30.12.2021Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii P_40_197/2016Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN 19.29.01.04
6 · The paper itself

Abstract

Fatty acids (FAs) have been shown to exhibit a pro-inflammatory response in various cell types, but astrocytes have been mostly overlooked. FAs, both saturated and unsaturated, have previously been shown to induce pro-inflammatory responses in astrocytes at high concentrations of hundreds of µg/mL. SSO (Sulfo-

Indexed as

fatty acids (FA)IL-6IL-8oleic acid (OA)palmitic acid (PA)pro-inflammation cytokines

Identifiers

PMID35448516
PMCPMC9031664
OpenAlexW4224252385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.