Evidence map›Paper›PMID 35448507›Full record

ArticleMetabolites2022

Probing Anti-Leukemic Metabolites from Marine-Derived

You-Ying Chen, Lo-Yun Chen, Po-Jen Chen, Mohamed El-Shazly, Bo-Rong Peng, Yu-Cheng Chen, Chun-Han Su, Jui-Hsin Su, Ping-Jyun Sung, Pei-Tzu Yen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Microorganisms · 2025
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  3. Article
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  5. Capnellenes fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

You-Ying ChenDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung City 80424, Taiwan.
Lo-Yun ChenGraduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Po-Jen ChenDepartment of Medical Research, E-Da Hospital, Kaohsiung City 82445, Taiwan.
Mohamed El-ShazlyDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Organization of African Unity Street, Abassia, Cairo 11566, Egypt.
Bo-Rong PengNational Museum of Marine Biology & Aquarium, Pingtung 94450, Taiwan.ORCID 0000-0002-4537-1353
Yu-Cheng ChenSepsis Research Center, Research Center of Tropical Medicine and Infectious Disease, Graduate Institute of Medicine, School of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chun-Han SuDepartment of Food Science, College of Human Ecology, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Jui-Hsin SuDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung City 80424, Taiwan.
Ping-Jyun SungDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung City 80424, Taiwan.ORCID 0000-0002-6644-9236
Pei-Tzu YenDepartment of Chinese Medicine, Sin-Lau Hospital, Tainan 70142, Taiwan.
Lung-Shuo WangDepartment of Chinese Medicine, Sin-Lau Hospital, Tainan 70142, Taiwan.ORCID 0000-0002-0020-8915
Kuei-Hung LaiGraduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-7220-6356
National Sun Yat-sen University · TWFu Jen Catholic University · TWSin-Lau Christian Hospital · TWAin Shams University · EGE-Da Hospital · TWNational Museum of Marine Biology and Aquarium · TWTaipei Medical University · TWTaipei Medical University Hospital · TW

Funding

Ministry of Education DP2-110-21121-01-N-12-03Ministry of Science and Technology 110-2320-B-038-034Taipei Medical University TMU109-AE1-B15
6 · The paper itself

Abstract

The unmet need for specific anti-leukemic agents for the treatment of acute lymphoblastic leukemia led us to screen a variety of marine-derived bacteria. The fermentation broth extract of

Indexed as

chromatographic bioassay profilediketopiperazinesstaurosporineStreptomyces sp. LY1209

Identifiers

PMID35448507
PMCPMC9025307
OpenAlexW4224309895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.