Evidence map›Paper›PMID 35448485›Full record

ArticleMetabolites2022

Volatilomics-Based Microbiome Evaluation of Fermented Dairy by Prototypic Headspace-Gas Chromatography-High-Temperature Ion Mobility Spectrometry (HS-GC-HTIMS) and Non-Negative Matrix Factorization (NNMF).

Charlotte C Capitain, Fatemeh Nejati, Martin Zischka, Markus Berzak, Stefan Junne, Peter Neubauer, Philipp Weller

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Charlotte C CapitainInstitute for Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.ORCID 0000-0002-7777-4368
Fatemeh NejatiBioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Ackerstrasse 76 ACK 24, 13355 Berlin, Germany.
Martin ZischkaInstitute for Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.
Markus BerzakInstitute for Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.
Stefan JunneBioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Ackerstrasse 76 ACK 24, 13355 Berlin, Germany.ORCID 0000-0001-6185-2627
Peter NeubauerBioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Ackerstrasse 76 ACK 24, 13355 Berlin, Germany.ORCID 0000-0002-1214-9713
Philipp WellerInstitute for Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.ORCID 0000-0002-5083-421X
Technische Hochschule Mannheim · DETechnische Universität Berlin · DE

Funding

Federal Ministry for Economic Affairs and Energy FZ4014707AW9
6 · The paper itself

Abstract

Fermented foods, such as yogurt and kefir, contain a versatile spectrum of volatile organic compounds (VOCs), including ethanol, acetic acid, ethyl acetate, and diacetyl. To overcome the challenge of overlapping peaks regarding these key compounds, the drift tube temperature was raised in a prototypic high-temperature ion mobility spectrometer (HTIMS). This HS-GC-HTIMS was used for the volatilomic profiling of 33 traditional kefir, 13 commercial kefir, and 15 commercial yogurt samples. Pattern recognition techniques, including principal component analysis (PCA) and NNMF, in combination with non-targeted screening, revealed distinct differences between traditional and commercial kefir while showing strong similarities between commercial kefir and yogurt. Classification of fermented dairy samples into commercial yogurt, commercial kefir, traditional mild kefir, and traditional tangy kefir was also possible for both PCA- and NNMF-based models, obtaining cross-validation (CV) error rates of 0% for PCA-LDA, PCA-

Indexed as

dairy fermentationgas chromatography–ion mobility spectroscopy (GC-IMS)high-temperature ion mobility spectrometry (HTIMS)non-negative matrix factorization (NNMF)non-targeted screening (NTS) using machine learningquantitative polymerase chain reaction (qPCR)traditional and commercial kefirvolatile organic compounds (VOCs)

Identifiers

PMID35448485
PMCPMC9025153
OpenAlexW4220980768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.