Evidence map›Paper›PMID 35448453›Full record

ArticleToxics2022

Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice.

Jiri Kassa, Christopher M Timperley, Mike Bird, A Christopher Green, John E H Tattersall

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jiri KassaDepartment of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, 60200 Brno, Czech Republic.ORCID 0000-0002-2957-269X
Christopher M TimperleyChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (DSTL), Salisbury SP4 0JQ, UK.
Mike BirdChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (DSTL), Salisbury SP4 0JQ, UK.
A Christopher GreenChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (DSTL), Salisbury SP4 0JQ, UK.
John E H TattersallChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (DSTL), Salisbury SP4 0JQ, UK.
Defence Science and Technology Laboratory · GBUniversity of Defence · CZ

Funding

Ministry of Defence Long-term organization development plan - Medical Aspects of Weapons of Mass Destruction
6 · The paper itself

Abstract

The therapeutic efficacy of treatments for acute intoxication with highly toxic organophosphorus compounds, called nerve agents, usually involves determination of LD

Indexed as

atropineMB327micenerve agentsoximes

Identifiers

PMID35448453
PMCPMC9027337
OpenAlexW4224212594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.