Evidence map›Paper›PMID 35448437›Full record

ArticleToxics2022

Long-Term Exposure to Air Pollution Associates the Risk of Benign Brain Tumor: A Nationwide, Population-Based, Cohort Study in Taiwan.

Kuang-Hsi Chang, Chieh-Lin Jerry Teng, Yi-Chao Hsu, Stella Chin-Shaw Tsai, Han-Jie Lin, Tsai-Ling Hsieh, Chih-Hsin Muo, Chung Y Hsu, Ruey-Hwang Chou

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. The Clinical and Molecular Profile of Lung Cancer Patients Harboring theInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Kuang-Hsi ChangDepartment of Medical Research, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.ORCID 0000-0002-4453-0068
Chieh-Lin Jerry TengDivision of Hematology/Medical Oncology, Department of Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan.ORCID 0000-0001-9744-0368
Yi-Chao HsuInstitute of Biomedical Sciences, Mackey Medical College, New Taipei City 252, Taiwan.ORCID 0000-0001-9071-475X
Stella Chin-Shaw TsaiDepartment of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.ORCID 0000-0003-2694-1207
Han-Jie LinDepartment of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.
Tsai-Ling HsiehDepartment of Medical Research, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.
Chih-Hsin MuoManagement Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan.
Chung Y HsuGraduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-5632-2733
Ruey-Hwang ChouThe Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung 404, Taiwan.
National Chung Hsing University · TWChina Medical University · TWTungs' Taichung MetroHarbor Hospital · TWAsia University · TWMackay Medical University · TW

Funding

China Medical University CMU110-MF-70China Medical University Hospital DMR-111-105Ministry of Science and Technology MOST 110-2320-B-039-031Taiwan Ministry of Health and Welfare Clinical Trial Center MOHW109-TDU-B-212-124004Tungs' Taichung Metro Harbor hospital research grant TTMHH-R1120013
6 · The paper itself

Abstract

Air pollutants as risk factors for benign brain tumor (BBT) remain unclear. Therefore, we conducted a nationwide retrospective cohort study by integrating the patients' clinical data and daily air quality data to assess the environmental risk factors of BBT in Taiwan.Daily air quality data were categorized into quartiles (Q1 to Q4). The adjusted hazard ratio (aHR) was evaluated by comparing the BBT incidence rate of the subjects in Q2-Q4 with that of the subjects in Q1 (the lowest concentration of air pollutants). A total of 161,213 subjects were enrolled in the study. Among the air pollutants tested, the aHR of BBT was significantly higher in the subjects who were exposed to the highest level (Q4) of CO (aHR 1.37, 95% CI 1.08-1.74), NO

Indexed as

air pollutionbenign brain tumor (BBT)carbon monoxide (CO)nitrogen dioxide (NO2)particulate matter (PM)

Identifiers

PMID35448437
PMCPMC9028167
OpenAlexW4224324383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.