Evidence map›Paper›PMID 35448434›Full record

ArticleToxics2022

Exposure to Air Pollutants Increases the Risk of Chronic Rhinosinusitis in Taiwan Residents.

Shih-Wei Chen, Han-Jie Lin, Stella Chin-Shaw Tsai, Cheng-Li Lin, Chung Y Hsu, Tsai-Ling Hsieh, Chuan-Mu Chen, Kuang-Hsi Chang

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Association between air pollution and allergic upper respiratory diseases: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Characterizing air pollution exposure methodologies in rhinology: a scoping review.International journal of environmental health research · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shih-Wei ChenDepartment of Life Sciences and Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.
Han-Jie LinDepartment of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.
Stella Chin-Shaw TsaiDepartment of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.ORCID 0000-0003-2694-1207
Cheng-Li LinManagement Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan.
Chung Y HsuGraduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-5632-2733
Tsai-Ling HsiehDepartment of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.
Chuan-Mu ChenDepartment of Life Sciences and Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0003-2461-9150
Kuang-Hsi ChangDepartment of Life Sciences and Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-4453-0068
National Chung Hsing University · TWChina Medical University · TWTungs' Taichung MetroHarbor Hospital · TW

Funding

China Medical University Hospital DMR-111-105Taiwan Ministry of Health and Welfare Clinical Trial Center MOHW109-TDU-B-212-124004Tungs' Taichung Metro Harbor hospital TTMHH-R1100012
6 · The paper itself

Abstract

Air pollution triggers a tissue-specific inflammatory response. However, studies on the association between exposure to air pollutants and chronic rhinosinusitis (CRS) risk remain limited. Thus, we conducted this nationwide study to define the association between air pollution and CRS. We used the Longitudinal Health Insurance Database (LHID) and Taiwan Air Quality-Monitoring Database (TAQMD) to conduct a population-based cohort study. Study participants were recruited from the LHID, a data subset of the National Health Insurance Research Database that randomly sampled one million individuals. TAQMD has been an air pollutant database since 1998. In univariate and multivariate Cox proportional hazards regression models, adjusted hazard ratios (aHRs) and 95% CIs of CRS in five air pollutants were accounted. We adjusted for age, sex, urbanization level, insurance fee, comorbidities, and pollutant levels in the multivariate model. The total number of participants enrolled in this study was 160,504. The average age was 40.46 ± 14.62 years; males constituted 43.8% of the total participants. The percentages of alcoholism, tobacco dependence, and COPD were 1.5%, 2.8%, and 28.3%, respectively. After adjustment for age, sex, urbanization level, insurance fee, and comorbidities, the highest levels of air pollutants, including PM

Indexed as

air pollutionchronic rhinosinusitislongitudinal health insurance databaseTaiwan air quality-monitoring database

Identifiers

PMID35448434
PMCPMC9031629
OpenAlexW4224309749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.