Evidence map›Paper›PMID 35448304›Full record

ReviewBiosensors2022

Graphene-Based Biosensors for Molecular Chronic Inflammatory Disease Biomarker Detection.

Isidro Badillo-Ramírez, Yojana J P Carreón, Claudia Rodríguez-Almazán, Claudia M Medina-Durán, Selene R Islas, José M Saniger

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Cardio Protective Role of Graphene-based FeCell biochemistry and biophysics · 2026
    Article
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Isidro Badillo-RamírezCenter for Intelligent Drug Delivery and Sensing Using Microcontainers and Nanomechanics (IDUN), Department of Health Technology, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.ORCID 0000-0002-9153-7158
Yojana J P CarreónInstituto de Ciencias Aplicadas y Tecnología, Universidad Nacional Autónoma de México, Av. Universidad 3000, Coyoacan, Mexico City 04510, Mexico.
Claudia Rodríguez-AlmazánInstituto de Ciencias Aplicadas y Tecnología, Universidad Nacional Autónoma de México, Av. Universidad 3000, Coyoacan, Mexico City 04510, Mexico.ORCID 0000-0002-8586-2317
Claudia M Medina-DuránInstituto de Ciencias Aplicadas y Tecnología, Universidad Nacional Autónoma de México, Av. Universidad 3000, Coyoacan, Mexico City 04510, Mexico.
Selene R IslasInstituto de Ciencias Aplicadas y Tecnología, Universidad Nacional Autónoma de México, Av. Universidad 3000, Coyoacan, Mexico City 04510, Mexico.ORCID 0000-0003-2257-469X
José M SanigerInstituto de Ciencias Aplicadas y Tecnología, Universidad Nacional Autónoma de México, Av. Universidad 3000, Coyoacan, Mexico City 04510, Mexico.ORCID 0000-0001-8024-2541
Universidad Nacional Autónoma de México · MX

Funding

Consejo Nacional de Ciencia y Tecnología FC-2016-2014UNAM-DGAPA PAPIIT-IT100721
6 · The paper itself

Abstract

Chronic inflammatory diseases, such as cancer, diabetes mellitus, stroke, ischemic heart diseases, neurodegenerative conditions, and COVID-19 have had a high number of deaths worldwide in recent years. The accurate detection of the biomarkers for chronic inflammatory diseases can significantly improve diagnosis, as well as therapy and clinical care in patients. Graphene derivative materials (GDMs), such as pristine graphene (G), graphene oxide (GO), and reduced graphene oxide (rGO), have shown tremendous benefits for biosensing and in the development of novel biosensor devices. GDMs exhibit excellent chemical, electrical and mechanical properties, good biocompatibility, and the facility of surface modification for biomolecular recognition, opening new opportunities for simple, accurate, and sensitive detection of biomarkers. This review shows the recent advances, properties, and potentialities of GDMs for developing robust biosensors. We show the main electrochemical and optical-sensing methods based on GDMs, as well as their design and manufacture in order to integrate them into robust, wearable, remote, and smart biosensors devices. We also describe the current application of such methods and technologies for the biosensing of chronic disease biomarkers. We also describe the current application of such methods and technologies for the biosensing of chronic disease biomarkers with improved sensitivity, reaching limits of detection from the nano to atto range concentration.

Indexed as

Biosensing TechniquesCOVID-19GraphiteBiomarkersChronic DiseaseElectrochemical TechniquesHumansBiomarkersGraphiteanalytical platformsbiomarkersbiosensorsgrapheneinflammatory diseases

Identifiers

PMID35448304
PMCPMC9030187
OpenAlexW4224130458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.