Evidence map›Paper›PMID 35448261›Full record

ArticleBiosensors2022

Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker.

Beatriz Jorge Coelho, Bruno Veigas, Luís Bettencourt, Hugo Águas, Elvira Fortunato, Rodrigo Martins, Pedro V Baptista, Rui Igreja

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Cell-Free Production Systems in Droplet Microfluidics.Advances in biochemical engineering/biotechnology · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beatriz Jorge CoelhoDepartment of Materials Science, School of Science and Technology, NOVA University of Lisbon and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.ORCID 0000-0003-3359-3773
Bruno VeigasAlmaScience, Campus da Caparica, 2829-519 Caparica, Portugal.
Luís BettencourtDepartment of Materials Science, School of Science and Technology, NOVA University of Lisbon and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.
Hugo ÁguasDepartment of Materials Science, School of Science and Technology, NOVA University of Lisbon and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.ORCID 0000-0001-7350-649X
Elvira FortunatoDepartment of Materials Science, School of Science and Technology, NOVA University of Lisbon and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.
Rodrigo MartinsDepartment of Materials Science, School of Science and Technology, NOVA University of Lisbon and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.ORCID 0000-0002-1997-7669
Pedro V BaptistaUCIBIO, I4HB, Life Sciences Department, School of Science and Technology, NOVA University of Lisbon, Campus de Caparica, 2829-516 Caparica, Portugal.ORCID 0000-0001-5255-7095
Rui IgrejaDepartment of Materials Science, School of Science and Technology, NOVA University of Lisbon and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.ORCID 0000-0002-6608-3422

Funding

Fundação para a Ciência e Tecnologia COVID/BD/152453/2022Fundação para a Ciência e Tecnologia LA/P/0037/2020Fundação para a Ciência e Tecnologia LA/P/0140/2020Fundação para a Ciência e Tecnologia PTDC/BTM-SAL/31201/2017Fundação para a Ciência e Tecnologia SFRH/BD/132904/2017Fundação para a Ciência e Tecnologia UIDB/04378/2020Fundação para a Ciência e Tecnologia UIDB/50025/2020Fundação para a Ciência e Tecnologia UIDP/04378/2020Fundação para a Ciência e Tecnologia UIDP/50025/2020
6 · The paper itself

Abstract

We introduce a digital microfluidics (DMF) platform specifically designed to perform a loop-mediated isothermal amplification (LAMP) of DNA and applied it to a real-time amplification to monitor a cancer biomarker,

Indexed as

MicrofluidicsNeoplasmsBiomarkers, TumorDNAFluorescent DyesHumansNucleic Acid Amplification TechniquesOligonucleotide Array Sequence AnalysisBiomarkers, TumorDNAFluorescent Dyescancer biomarkerdigital microfluidicsfluorescence detectionloop-mediated isothermal amplificationreal-time nucleic acid amplification monitoring

Identifiers

PMID35448261
PMCPMC9028060

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.