Evidence map›Paper›PMID 35448179›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

EGFR Targeting TKI-Related Skin Toxicities in a Patient with Darker Skin: A Case Report.

Arman Zereshkian, Alia Thawer, David M Hwang, Susanna Cheng

Open access · goldAbstract readCase Reports
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Arman ZereshkianDepartment of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada.
Alia ThawerOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
David M HwangLaboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON M4N 3M5, Canada.
Susanna ChengDepartment of Medical Oncology and Hematology, Sunnybrook Odette Cancer Centre, Sunnybrook Health Science Centre, Toronto, ON M4N 3M5, Canada.
Sunnybrook Health Science Centre · CAHealth Sciences Centre · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor receptor (EGFR) targeting tyrosine kinase inhibitors (TKIs) can result in significant skin toxicities that may impact patients' quality of life. While these skin reactions are well documented in patients with lighter skin, there is a paucity of literature and images to guide clinicians in their assessment in patients with darker skin tones. Given that dermatological reactions in patients with darker skin are not well represented, this can result in the undertreatment or mistreatment of these otherwise common toxicities. Herein, we present a case of a female patient with a darker skin tone with metastatic non-small cell lung carcinoma (NSCLC) with EGFR-TKI-related skin toxicity and her clinical course.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsErbB ReceptorsFemaleHumansProtein Kinase InhibitorsQuality of LifeEGFR protein, humanErbB ReceptorsProtein Kinase Inhibitorsdark skin toneEGFR inhibitorslung cancerskin toxicityTKI

Identifiers

PMID35448179
PMCPMC9028593
OpenAlexW4224316581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.