Evidence map›Paper›PMID 35448154›Full record

Trial reportCurrent oncology (Toronto, Ont.)2022

Engaging Patients in Smoking Cessation Treatment within the Lung Cancer Screening Setting: Lessons Learned from an NCI SCALE Trial.

Randi M Williams, Ellie Eyestone, Laney Smith, Joanna G Philips, Julia Whealan, Marguerite Webster, Tengfei Li, George Luta, Kathryn L Taylor, On Behalf Of The Lung Screening Tobacco Health Trial

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03200236 (Integrating Evidence-Based Smoking Cessation Interventions Into Lung Cancer Screening Programs), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03200236 phase3completednot on this map

Integrating Evidence-Based Smoking Cessation Interventions Into Lung Cancer Screening Programs: A Randomized Trial

TypeinterventionalSponsorGeorgetown UniversityRan2017 to 2022Enrolled1,114ConditionsSmoking, Tobacco, Tobacco-Related Carcinoma, Tobacco Use, Lung Cancer ScreeningArmsIntensive Telephone Counseling (8 sessions) with nicotine replacement, Usual Care: Telephone counseling (3 sessions) with nicotine replacement
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Updates in Lung Cancer Screening: A Decade of Evidence.Seminars in respiratory and critical care medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Randi M WilliamsCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0003-0837-9281
Ellie EyestoneCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
Laney SmithCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
Joanna G PhilipsCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
Julia WhealanCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0001-5826-8913
Marguerite WebsterCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
Tengfei LiDepartment of Biostatistics, Bioinformatics and Biomathematics, Georgetown University, Washington, DC 20007, USA.ORCID 0000-0002-5026-1773
George LutaDepartment of Biostatistics, Bioinformatics and Biomathematics, Georgetown University, Washington, DC 20007, USA.ORCID 0000-0002-4035-7632
Kathryn L TaylorCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
On Behalf Of The Lung Screening Tobacco Health Trial

Funding

Integrating Evidence-Based Smoking Cessation Interventions into Lung Cancer Screening Programs: A Randomized TrialR01CA207228 · NCI · GEORGETOWN UNIVERSITY · PI TAYLOR, KATHRYN L · 2016 to 2020
$3.5M
A Multilevel intervention to address health disparities in lung cancer screeningK99CA256515 · NCI · GEORGETOWN UNIVERSITY · PI WILLIAMS, RANDI M. · 2021 to 2022
$236k
NCI NIH HHS K99CA256515NCI NIH HHS R01CA207228
6 · The paper itself

Abstract

Offering smoking cessation treatment at lung cancer screening (LCS) will maximize mortality reduction associated with screening, but predictors of treatment engagement are not well understood. We examined participant characteristics of engagement in an NCI SCALE cessation trial. Eligible LCS patients (N = 818) were randomized to the Intensive arm (8 phone counseling sessions +8 weeks of nicotine replacement therapy (NRT)) vs. Minimal arm (3 sessions + 2 weeks of NRT). Engagement was measured by number of sessions completed (none, some, or all) and NRT mailed (none vs. any) in each arm. In the Intensive arm, those with ≥some college (OR = 2.1, 95% CI = 1.1, 4.0) and undergoing an annual scan (OR = 2.1, 95% CI = 1.1, 4.2) engaged in some counseling vs. none. Individuals with higher nicotine dependence were more likely (OR = 2.8, 95% CI = 1.3, 6.2) to request NRT. In the Minimal arm, those with higher education (OR = 2.1, 95% CI = 1.1, 3.9) and undergoing an annual scan (OR = 2.0, 95% CI = 1.04, 3.8) completed some sessions vs. none. Requesting NRT was associated with more pack-years (OR = 1.9, 95% CI = 1.1, 3.5). Regardless of treatment intensity, additional strategies are needed to engage those with lower education, less intensive smoking histories, and undergoing a first scan. These efforts will be important given the broader 2021 LCS guidelines.

Indexed as

Lung NeoplasmsSmoking CessationCounselingEarly Detection of CancerHumansTobacco Use Cessation Devicesintervention engagementlung cancer screeningsmoking cessationtobacco treatment

Identifiers

PMID35448154
PMCPMC9027703

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.