Evidence map›Paper›PMID 35448022›Full record

ArticleBrain sciences2022

Gender Influences Virtual Reality-Based Recovery of Cognitive Functions in Patients with Traumatic Brain Injury: A Secondary Analysis of a Randomized Clinical Trial.

Roberta Bruschetta, Maria Grazia Maggio, Antonino Naro, Irene Ciancarelli, Giovanni Morone, Francesco Arcuri, Paolo Tonin, Gennaro Tartarisco, Giovanni Pioggia, Antonio Cerasa and 1 more

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roberta BruschettaInstitute for Biomedical Research and Innovation (IRIB), National Research Council of Italy, 98164 Messina, Italy.ORCID 0000-0002-8778-2775
Maria Grazia MaggioDepartment of Biomedical and Biotechnological Science, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-0757-2389
Antonino NaroStroke Unit, Azienda Ospedaliera Universitaria Gaetano Martino, 98123 Messina, Italy.
Irene CiancarelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Giovanni MoroneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-3602-4197
Francesco ArcuriS'Anna Institute, 88900 Crotone, Italy.ORCID 0000-0002-7104-6378
Paolo ToninS'Anna Institute, 88900 Crotone, Italy.ORCID 0000-0002-4867-1378
Gennaro TartariscoInstitute for Biomedical Research and Innovation (IRIB), National Research Council of Italy, 98164 Messina, Italy.ORCID 0000-0001-9467-2024
Giovanni PioggiaInstitute for Biomedical Research and Innovation (IRIB), National Research Council of Italy, 98164 Messina, Italy.ORCID 0000-0002-8089-7449
Antonio CerasaInstitute for Biomedical Research and Innovation (IRIB), National Research Council of Italy, 98164 Messina, Italy.
Rocco Salvatore CalabròIRCCS Centro Neurolesi "Bonino Pulejo", 98124 Messina, Italy.ORCID 0000-0002-8566-3166

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rehabilitation of cognitive deficits in individuals with traumatic brain injury is essential for promoting patients' recovery and autonomy. Virtual reality (VR) training is a powerful tool for reaching this target, although the effectiveness of this intervention could be interfered with by several factors. In this study, we evaluated if demographical and clinical variables could be related to the recovery of cognitive function in TBI patients after a well-validated VR training. One hundred patients with TBI were enrolled in this study and equally randomized into the Traditional Cognitive Rehabilitation Group (TCRG: n = 50) or Virtual Reality Training Group (VRTG: n = 50). The VRTG underwent a VRT with BTs-N, whereas the TCRG received standard cognitive treatment. All the patients were evaluated by a complete neuropsychological battery before (T0) and after the end of the training (T1). We found that the VR-related improvement in mood, as well as cognitive flexibility, and selective attention were influenced by gender. Indeed, females who underwent VR training were those showing better cognitive recovery. This study highlights the importance of evaluating gender effects in planning cognitive rehabilitation programs. The inclusion of different repetitions and modalities of VR training should be considered for TBI male patients.

Indexed as

cognitive recoverygenderneurorehabilitationtraumatic brain injuryvirtual reality

Identifiers

PMID35448022
PMCPMC9024763

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.