Evidence map›Paper›PMID 35447910›Full record

ArticleMarine drugs2022

Identification of New CTX Analogues in Fish from the Madeira and Selvagens Archipelagos by Neuro-2a CBA and LC-HRMS.

Àngels Tudó, Maria Rambla-Alegre, Cintia Flores, Núria Sagristà, Paloma Aguayo, Laia Reverté, Mònica Campàs, Neide Gouveia, Carolina Santos, Karl B Andree and 3 more

Abstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Benthic DinoflagellateMarine drugs · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Àngels TudóInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.ORCID 0000-0001-7049-9116
Maria Rambla-AlegreInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.ORCID 0000-0003-4276-276X
Cintia FloresMass Spectrometry Laboratory, Organic Pollutants, IDAEA-CSIC, Jordi Girona 18, 08034 Barcelona, Spain.ORCID 0000-0002-7766-5639
Núria SagristàInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.
Paloma AguayoInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.
Laia RevertéInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.
Mònica CampàsInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.ORCID 0000-0002-1220-7100
Neide GouveiaRegional Fisheries Management-Madeira Government, Direção de Serviços de Investigação das Pescas (DSI-DRP), Estrada da Pontinha, 9004-562 Funchal, Portugal.
Carolina SantosInstituto das Florestas e Conservação da Natureza, IP-RAM, Secretaria Regional do Ambiente e Recursos Naturais, Regional Government of Madeira, IFCN IP-RAM, 9050-027 Funchal, Portugal.
Karl B AndreeInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.ORCID 0000-0001-6564-0015
Antonio MarquesPortuguese Institute of Sea and Atmosphere (IPMA), Division of Aquaculture, Seafood Upgrading and Bioprospection (DivAV), Avenida de Brasília, 1449-006 Lisbon, Portugal.ORCID 0000-0001-6745-745X
Josep CaixachMass Spectrometry Laboratory, Organic Pollutants, IDAEA-CSIC, Jordi Girona 18, 08034 Barcelona, Spain.
Jorge DiogèneInstitute of Agrifood Research and Technology (IRTA), Marine and Continental Waters Program, Carretera de Poble Nou, 43540 La Ràpita, Spain.ORCID 0000-0002-6567-6891

Funding

European Union Seventh Framework Programme 311820
6 · The paper itself

Abstract

Ciguatera Poisoning (CP) is caused by consumption of fish or invertebrates contaminated with ciguatoxins (CTXs). Presently CP is a public concern in some temperate regions, such as Macaronesia (North-Eastern Atlantic Ocean). Toxicity analysis was performed to characterize the fish species that can accumulate CTXs and improve understanding of the ciguatera risk in this area. For that, seventeen fish specimens comprising nine species were captured from coastal waters inMadeira and Selvagens Archipelagos. Toxicity was analysed by screening CTX-like toxicity with the neuroblastoma cell-based assay (neuro-2a CBA). Afterwards, the four most toxic samples were analysed with liquid chromatography-high resolution mass spectrometry (LC-HRMS). Thirteen fish specimens presented CTX-like toxicity in their liver, but only four of these in their muscle. The liver of one specimen of

Indexed as

Ciguatera PoisoningCiguatoxinsAnimalsChromatography, LiquidFishesMass SpectrometryCiguatoxinsCBAciguateraciguatoxinfishLC-HRMSliver

Identifiers

PMID35447910
PMCPMC9031360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.