Evidence map›Paper›PMID 35447882›Full record

ArticleInfectious disease reports2022

Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19.

Yuto Yasuda, Satoru Mutsuo, Motoaki Hamada, Kazuo Murai, Yutaka Hirayama, Kiyoshi Uemasu, Soichi Arasawa, Daisuke Iwashima, Ken-Ichi Takahashi

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuto YasudaDepartment of Respiratory Medicine, Kishiwada City Hospital, 1001 Gakuhara-cho, Kishiwada-shi 586-8501, Japan.ORCID 0000-0002-5703-4119
Satoru MutsuoDepartment of Central Clinical Laboratory, Kishiwada City Hospital, 1001 Gakuhara-cho, Kishiwada-shi 586-8501, Japan.
Motoaki HamadaDepartment of Research and Development, Dawn Inc., 1-13-5 Ayabe Bld.3F-B, Isehara-shi 259-1131, Japan.
Kazuo MuraiDepartment of Engineering, Dawn Inc., 1-13-5 Ayabe Bld.3F-B, Isehara-shi 259-1131, Japan.
Yutaka HirayamaDepartment of Respiratory Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho Shogoin Sakyoku, Kyoto 606-8507, Japan.
Kiyoshi UemasuDepartment of Respiratory Medicine, Kishiwada City Hospital, 1001 Gakuhara-cho, Kishiwada-shi 586-8501, Japan.ORCID 0000-0002-5818-3028
Soichi ArasawaDepartment of Gastroenterology, Kishiwada City Hospital, 1001 Gakuhara-cho, Kishiwada-shi 586-8501, Japan.
Daisuke IwashimaDepartment of Respiratory Medicine, Kishiwada City Hospital, 1001 Gakuhara-cho, Kishiwada-shi 586-8501, Japan.ORCID 0000-0001-5554-5401
Ken-Ichi TakahashiDepartment of Respiratory Medicine, Kishiwada City Hospital, 1001 Gakuhara-cho, Kishiwada-shi 586-8501, Japan.
Kishiwada City Hospital · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAluminium reduces severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival in experimental settings. It is unknown whether adding an aluminium gauze to a mask reduces the SARS-CoV-2 RNA load in the mask and whether SARS-CoV-2 is detectable in the breath that permeates through such a mask in clinical settings.

methodsPatients admitted to Kishiwada City Hospital, Osaka, Japan, between July 2021 and September 2021 were enrolled in the study. Non-woven masks comprising filters with 99% viral filtration efficacy and aluminium and cotton gauzes attached to plastic collection cases were developed. All participants wore the experimental mask models for three hours.

resultsTwenty-nine patients who wore the final model masks were analysed in this study. The Ct values of the nucleocapsid gene and envelope gene of SARS-CoV-2 were significantly higher in the aluminium gauze than in the cotton gauze. SARS-CoV-2 RNA was detected in the masks of 8 out of 12 vaccinated patients (66.7%). Although breath condensates were collected behind both aluminium and cotton gauzes, SARS-CoV-2 RNA was not detected in these condensates.

conclusionsOur study indicated that non-woven masks with an aluminium gauze may obstruct SARS-CoV-2 transmission in clinical settings better than non-woven masks with cotton gauzes.

Indexed as

aluminiumCOVID-19non-woven maskPCRSARS-CoV-2

Identifiers

PMID35447882
PMCPMC9028381
OpenAlexW4224306684

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.