Evidence map›Paper›PMID 35447855›Full record

ArticleClinics and practice2022

Usefulness and Limits of Tractography for Surgery in the Precentral Gyrus-A Case Report.

Tim Wende, Florian Wilhelmy, Johannes Kasper, Gordian Prasse, Christian Franke, Felix Arlt, Clara Frydrychowicz, Jürgen Meixensberger, Ulf Nestler

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinics and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tim WendeDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.ORCID 0000-0002-8634-8897
Florian WilhelmyDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Johannes KasperDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.ORCID 0000-0003-2122-2676
Gordian PrasseInstitute of Neuroradiology, University Hospital Leipzig, 04103 Leipzig, Germany.
Christian FrankeDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Felix ArltDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.ORCID 0000-0003-3749-2494
Clara FrydrychowiczInstitute of Neuropathology, University Hospital Leipzig, 04103 Leipzig, Germany.
Jürgen MeixensbergerDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Ulf NestlerDepartment of Neurosurgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.ORCID 0000-0002-2963-4344
University Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The resection of tumors within the primary motor cortex is a constant challenge. Although tractography may help in preoperative planning, it has limited application. While it can give valuable information on subcortical fibers, it is less accurate in the cortical layer of the brain. A 38-year-old patient presented with paresis of the right hand and focal epileptic seizures due to a tumor in the left precentral gyrus. Transcranial magnetic stimulation was not applicable due to seizures, so microsurgical resection was performed with preoperative tractography and intraoperative direct electrical stimulation. A histopathological assessment revealed a diagnosis of glioblastoma. Postoperative magnetic resonance imaging (MRI) showed complete resection. The paresis dissolved completely during follow-up. Surgery within the precentral gyrus is of high risk and requires multimodal functional planning. If interpreted with vigilance and consciousness of the underlying physical premises, tractography can provide helpful information within its limitations, which is especially subcortically. However, it may also help in the identification of functional cortex columns of the brain in the presence of a tumor.

Indexed as

direct electrical stimulationglioblastomaprecentral gyrustractographytranscranial magnetic stimulation

Identifiers

PMID35447855
PMCPMC9025938
OpenAlexW4223593933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.