Evidence map›Paper›PMID 35447701›Full record

ArticleBioengineering (Basel, Switzerland)2022

Smart-Data-Driven System for Alzheimer Disease Detection through Electroencephalographic Signals.

Teresa Araújo, João Paulo Teixeira, Pedro Miguel Rodrigues

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  11. Novel methodology for detection and prediction of mild cognitive impairment using resting-state EEG.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Teresa AraújoCBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua de Diogo Botelho 1327, 4169-005 Porto, Portugal.
João Paulo TeixeiraCEDRI-Research Centre in Digitalization and Intelligent Robotics and UNIAG-Management Applied Research Unit, Instituto Politécnico de Bragança (IPB), Braganca, Campus de Sta Apolónia, Apartado 134, 5301-857 Bragança, Portugal.ORCID 0000-0002-6679-5702
Pedro Miguel RodriguesCBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua de Diogo Botelho 1327, 4169-005 Porto, Portugal.ORCID 0000-0002-5381-6615
Universidade Católica Portuguesa · PTPolytechnic Institute of Bragança · PT

Funding

Fundação para a Ciência e Tecnologia UIDB/50016/2020 and UIDB/05757/2020
6 · The paper itself

Abstract

backgroundAlzheimer's Disease (AD) stands out as one of the main causes of dementia worldwide and it represents around 65% of all dementia cases, affecting mainly elderly people. AD is composed of three evolutionary stages: Mild Cognitive Impairment (MCI), Mild and Moderate AD (ADM) and Advanced AD (ADA). It is crucial to create a tool for assisting AD diagnosis in its early stages with the aim of halting the disease progression.

methodsThe main purpose of this study is to develop a system with the ability of differentiate each disease stage by means of Electroencephalographic Signals (EEG). Thereby, an EEG nonlinear multi-band analysis by Wavelet Packet was performed enabling to extract several features from each study group. Classic Machine Learning (ML) and Deep Learning (DL) methods have been used for data classification per EEG channel.

resultsThe maximum accuracies obtained were 78.9% (Healthy controls (C) vs. MCI), 81.0% (C vs. ADM), 84.2% (C vs. ADA), 88.9% (MCI vs. ADM), 93.8% (MCI vs. ADA), 77.8% (ADM vs. ADA) and 56.8% (All vs. All).

conclusionsThe proposed method outperforms previous studies with the same database by 2% in binary comparison MCI vs. ADM and central and parietal brain regions revealed abnormal activity as AD progresses.

Indexed as

Alzheimer diseaseclassic machine learningclassificationdeep learningelectroencephalographic signalsnonlinear multi-band analysiswavelet packet

Identifiers

PMID35447701
PMCPMC9031324
OpenAlexW4221056805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.