Evidence map›Paper›PMID 35447380›Full record

Observational studyJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2022

Clinical Characteristics of Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19.

Marija Stamenković, Ljiljana Radmilo, Mirjana Jovićević, Tamara Rabi-Žikić, Marija Žarkov, Svetlana Ružička-Kaloci, Svetlana Simić, Aleksandar Stamenković, Jelena Dangić, Goran Knezović and 1 more

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Correspondence on "Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19".Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  7. Response to the Letter to the Editor by Mungmunpuntipantip et al.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marija StamenkovićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia. Electronic address: novisad56@gmail.com.
Ljiljana RadmiloThe General Hospital "Dr Radivoj Simonović" Sombor, Serbia.
Mirjana JovićevićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Tamara Rabi-ŽikićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Marija ŽarkovClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Svetlana Ružička-KalociClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Svetlana SimićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Aleksandar StamenkovićInstitute for Biocides and Medical Ecology, Belgrade, Serbia.
Jelena DangićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia.
Goran KnezovićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia.
Željko ŽivanovićClinic of Neurology, Clinical Center of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
University of Novi Sad · RSKlinički centar Vojvodine · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to examine the clinical characteristics of patients with acute ischemic stroke which were previously vaccinated against Coronavirus Disease 2019 (COVID-19) and determine whether the vaccine had impact on outcome. MATERIALS AND

methodsIn this observational cohort study we analyzed the clinical characteristics of 58 patients with ischemic stroke, previously vaccinated against COVID-19. We analyzed demographic characteristics, risk factors, type of stroke and outcome. We also compared outcome of those patients with outcome in stroke patients hospitalized in the same period but not vaccinated, patients hospitalized during the pandemic, before vaccination began, and stroke patients hospitalized before the pandemic. Further, we compared mortality rate with mortality rate in patients who had acute ischemic stroke and COVID-19 simultaneously.

resultsThe mean age of the patients was 71.0 years, most were male (58.6%), mostly with risk factors for stroke. In the largest number of patients, 17 (29.3%), the etiopathogenetic mechanism of stroke was atherosclerosis of the large arteries. Mortality in vaccinated patients was identical to mortality in stroke patients before pandemic, without significant difference from mortality in unvaccinated patients (13.8% versus 8.6%; p= 0.23). The mean NIHSS and mRS score at discharge for all examined groups were without significant difference. A significant difference in mortality was found between COVID-19 positive and COVID-19 negative stroke patients (37.8% versus 18.1%; p=0.001).

conclusionsThere are no significant differences in clinical characteristics of stroke in vaccinated compared to unvaccinated patients. We did not find a connection between vaccination and stroke.

Indexed as

COVID-19Ischemic StrokeStrokeAgedFemaleHospitalizationHumansMalePandemicsClinical presentationCovid-19Ischemic strokeVaccines

Identifiers

PMID35447380
PMCPMC8977441
OpenAlexW4224317008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.