Evidence map›Paper›PMID 35447086›Full record

ArticleCurrent biology : CB2022

Interneuron control of C. elegans developmental decision-making.

Cynthia M Chai, Mahdi Torkashvand, Maedeh Seyedolmohadesin, Heenam Park, Vivek Venkatachalam, Paul W Sternberg

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. A multilayered gap junction network is essential for social decision-making.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Semantic Representation of Neural Circuit Knowledge inbioRxiv : the preprint server for biology · 2023
    Article
  13. Calumenin, a CaBiology · 2023
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cynthia M ChaiDivision of Biology and Biological Engineering, California Institute of Technology, 1200 E California Blvd, Pasadena, CA 91125, USA. Electronic address: cchai@caltech.edu.
Mahdi TorkashvandDepartment of Physics, Northeastern University, 360 Huntington Ave, Boston, MA 02115, USA.
Maedeh SeyedolmohadesinDepartment of Physics, Northeastern University, 360 Huntington Ave, Boston, MA 02115, USA.
Heenam ParkDivision of Biology and Biological Engineering, California Institute of Technology, 1200 E California Blvd, Pasadena, CA 91125, USA.
Vivek VenkatachalamDepartment of Physics, Northeastern University, 360 Huntington Ave, Boston, MA 02115, USA. Electronic address: v.venkatachalam@northeastern.edu.
Paul W SternbergDivision of Biology and Biological Engineering, California Institute of Technology, 1200 E California Blvd, Pasadena, CA 91125, USA. Electronic address: pws@caltech.edu.
California Institute of Technology · USNortheastern University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Enhancing the C. elegans animal resource through genome editingR24OD023041 · OD · UNIVERSITY OF MINNESOTA · PI ROUGVIE, ANN E., STERNBERG, PAUL WARREN · 2017 to 2024
$5.1M
Comprehensive Analysis of a Decision CircuitUF1NS111697 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PEHLEVAN, CENGIZ, SAMUEL, ARAVINTHAN D. · 2019 to 2019
$3.0M
Development and Divergence of Whole-Brain ActivityR01NS126334 · NINDS · NORTHEASTERN UNIVERSITY · PI Vivek Venkatachalam · 2022 to 2026
$2.1M
Bipartite gene expression system for C. elegans genetic and neural circuit analysisR21MH115454 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI STERNBERG, PAUL WARREN · 2017 to 2018
$454k
NIH HHS P40 OD010440NIH HHS R24 OD023041NIMH NIH HHS R21 MH115454NINDS NIH HHS R01 NS126334NINDS NIH HHS UF1 NS111697
6 · The paper itself

Abstract

Natural environments are highly dynamic, and this complexity challenges animals to accurately integrate external cues to shape their responses. Adaptive developmental plasticity enables organisms to remodel their physiology, morphology, and behavior to better suit the predicted future environment and ultimately enhance their ecological success.

Indexed as

Caenorhabditis elegans ProteinsNeuropeptidesAnimalsCaenorhabditis elegansInterneuronsPheromonesSensory Receptor CellsCaenorhabditis elegans ProteinsNeuropeptidesPheromonescircuitsdevelopmental plasticityG-protein coupled receptorinterneuronmetabolismmetabotropic glutamate receptorneuropeptidepheromonephysiology

Identifiers

PMID35447086
PMCPMC9270850
OpenAlexW4225892120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.