Evidence map›Paper›PMID 35446872›Full record

ArticlePloS one2022

Benefits of integrated screening and vaccination for infection control.

Marie Jeanne Rabil, Sait Tunc, Douglas R Bish, Ebru K Bish

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marie Jeanne RabilGrado Department of Industrial and Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States of America.ORCID 0000-0003-0267-7026
Sait TuncGrado Department of Industrial and Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States of America.
Douglas R BishDepartment of Information Systems, Statistics, and Management Science, Culverhouse College of Business, The University of Alabama, Tuscaloosa, AL, United States of America.
Ebru K BishDepartment of Information Systems, Statistics, and Management Science, Culverhouse College of Business, The University of Alabama, Tuscaloosa, AL, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceScreening and vaccination are essential in the fight against infectious diseases, but need to be integrated and customized based on community and disease characteristics.

objectiveTo develop effective screening and vaccination strategies, customized for a college campus, to reduce COVID-19 infections, hospitalizations, deaths, and peak hospitalizations. DESIGN, SETTING, AND

participantsWe construct a compartmental model of disease spread under vaccination and routine screening, and study the efficacy of four mitigation strategies (routine screening only, vaccination only, vaccination with partial or full routine screening), and a no-intervention strategy. The study setting is a hypothetical college campus of 5,000 students and 455 faculty members during the Fall 2021 academic semester, when the Delta variant was the predominant strain. For sensitivity analysis, we vary the screening frequency, daily vaccination rate, initial vaccine coverage, and screening and vaccination compliance; and consider scenarios that represent low/medium/high transmission and test efficacy. Model parameters come from publicly available or published sources.

resultsWith low initial vaccine coverage (30% in our study), even aggressive vaccination and screening result in a high number of infections: 1,020 to 2,040 (1,530 to 2,480) with routine daily (every other day) screening of the unvaccinated; 280 to 900 with daily screening extended to the newly vaccinated in base- and worst-case scenarios, which respectively consider reproduction numbers of 4.75 and 6.75 for the Delta variant.

conclusionIntegrated vaccination and routine screening can allow for a safe opening of a college when both the vaccine effectiveness and the initial vaccine coverage are sufficiently high. The interventions need to be customized considering the initial vaccine coverage, estimated compliance, screening and vaccination capacity, disease transmission and adverse outcome rates, and the number of infections/peak hospitalizations the college is willing to tolerate.

Indexed as

COVID-19VaccinesHumansInfection ControlSARS-CoV-2VaccinationVaccines

Identifiers

PMID35446872
PMCPMC9023060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.