Evidence map›Paper›PMID 35446718›Full record

ArticleAnnals of the Royal College of Surgeons of England2023

The impact of age on long-term survival following gastrectomy for gastric cancer.

L R Brown, S K Kamarajah, A Madhavan, S Wahed, M Navidi, A Immanuel, N Hayes, A W Phillips

Abstract read
In one paragraph

Article in Annals of the Royal College of Surgeons of England, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

L R BrownThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
S K KamarajahThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
A MadhavanThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
S WahedThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
M NavidiThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
A ImmanuelThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
N HayesThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
A W PhillipsThe Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGastrectomy remains the primary curative treatment modality for patients with gastric cancer. Concerns exist about offering surgery with a high associated morbidity and mortality to elderly patients. The study aimed to evaluate the long-term survival of patients with gastric cancer who underwent gastrectomy comparing patients aged <70 years with patients aged ≥70 years.

methodsConsecutive patients who underwent gastrectomy for adenocarcinoma with curative intent between January 2000 and December 2017 at a single centre were included. Patients were stratified by age with a cut-off of 70 years used to create two cohorts. Log rank test was used to compare overall survival and Cox multivariable regression used to identify predictors of long-term survival.

resultsDuring the study period, 959 patients underwent gastrectomy, 520 of whom (54%) were aged ≥70 years. Those aged <70 years had significantly lower American Society of Anesthesiologists grades (

conclusionsLow postoperative mortality and good long-term survival were demonstrated for both age groups following gastrectomy. Age ≥70 years was, however, associated with poorer outcomes. This should be regarded as important factor when counselling patients regarding treatment options.

Indexed as

Stomach NeoplasmsAgedGastrectomyHumansPostoperative ComplicationsProportional Hazards ModelsRetrospective StudiesSurvival RateAdenocarcinomaAgedGastrectomyStomach neoplasms

Identifiers

PMID35446718
PMCPMC9974338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.