Evidence map›Paper›PMID 35446632›Full record

ArticleScience (New York, N.Y.)2022

Cell division in tissues enables macrophage infiltration.

Maria Akhmanova, Shamsi Emtenani, Daniel Krueger, Attila Gyoergy, Mariana Guarda, Mikhail Vlasov, Fedor Vlasov, Andrei Akopian, Aparna Ratheesh, Stefano De Renzis and 1 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Blocking the mCellular & molecular immunology · 2026
    Article
  2. Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Rapid Preparation of Living Drosophila Pupal Macrophages for Ex Vivo Imaging.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  16. Macrophage polarization in inflammatory bowel disease.Cell communication and signaling : CCS · 2023
    Review
  17. Review
  18. Review
  19. Epithelial multicellular clustering enabled by polarized macrophages on soft matrices.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Maria AkhmanovaInstitute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.ORCID 0000-0003-1522-3162
Shamsi EmtenaniInstitute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.
Daniel Krueger *Developmental Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID 0000-0003-1139-7755
Attila Gyoergy *Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.ORCID 0000-0002-1819-198X
Mariana GuardaInstitute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.ORCID 0000-0001-8238-480X
Mikhail VlasovBundesgymnasium Klosterneuburg, Klosterneuburg, Austria.
Fedor VlasovBundesgymnasium Klosterneuburg, Klosterneuburg, Austria.
Andrei AkopianBundesgymnasium Klosterneuburg, Klosterneuburg, Austria.
Aparna RatheeshInstitute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.ORCID 0000-0001-7190-0776
Stefano De RenzisDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Daria E SiekhausInstitute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.ORCID 0000-0001-8323-8353
Institute of Science and Technology Austria · ATEuropean Molecular Biology Laboratory · DE

Funding

Austrian Science Fund FWF M 2379
6 · The paper itself

Abstract

Cells migrate through crowded microenvironments within tissues during normal development, immune response, and cancer metastasis. Although migration through pores and tracks in the extracellular matrix (ECM) has been well studied, little is known about cellular traversal into confining cell-dense tissues. We find that embryonic tissue invasion by

Indexed as

Focal AdhesionsIntegrinsAnimalsCell AdhesionCell DivisionCell MovementDrosophilaExtracellular MatrixMacrophagesIntegrins

Identifiers

PMID35446632
OpenAlexW4225392289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.