Evidence map›Paper›PMID 35446241›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Toll-Interacting Protein and Altered Lung Microbiota in Idiopathic Pulmonary Fibrosis.

Jay H Lipinski, John R Erb-Downward, Gary B Huffnagle, Kevin R Flaherty, Fernando J Martinez, Bethany B Moore, Robert P Dickson, Imre Noth, David N O'Dwyer

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The lung microbiome in interstitial lung disease.Breathe (Sheffield, England) · 2025
    Review
  6. Article
  7. Commensal Oral Microbiota, Disease Severity, and Mortality in Fibrotic Lung Disease.American journal of respiratory and critical care medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jay H LipinskiUniversity of Michigan Ann Arbor, Michigan.
John R Erb-DownwardUniversity of Michigan Ann Arbor, Michigan.
Gary B HuffnagleUniversity of Michigan Ann Arbor, Michigan.
Kevin R FlahertyUniversity of Michigan Ann Arbor, Michigan.
Fernando J MartinezCornell University New York, New York.
Bethany B MooreUniversity of Michigan Ann Arbor, Michigan.
Robert P DicksonUniversity of Michigan Ann Arbor, Michigan.ORCID 0000-0002-6875-4277
Imre NothUniversity of Virginia Charlottesville, Virginia.
David N O'DwyerUniversity of Michigan Ann Arbor, Michigan.ORCID 0000-0003-3214-380X
University of Michigan · USCornell University · USUniversity of Virginia · US

Funding

1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyUH3HL145266 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J, NOTH, IMRE · 2021 to 2025
$11.6M
Immunobiology of Lung Injury and FibrosisR35HL144481 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2019 to 2024
$5.2M
Architectural structure and regulation of TOLLIP in IPFR01HL130796 · NHLBI · UNIVERSITY OF VIRGINIA · PI NOTH, IMRE · 2016 to 2019
$3.1M
The role of the lung microbiome in oxygen-induced lung injuryR01HL144599 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DICKSON, ROBERT PICKETT · 2019 to 2023
$2.1M
Toll-like Receptors and Respiratory Microbiota Interactions in Idiopathic PulmonaryR00HL139996 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'DWYER, DAVID NOEL · 2020 to 2022
$747k
Midcareer Investigator Award in Patient-Oriented Research in the Microbiome and Lung DiseaseK24HL159247 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 2022 to 2026
$625k
Gut Microbiota and Host Regulatory Cross-Talk in Pulmonary FibrosisR56HL155055 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'DWYER, DAVID NOEL · 2021 to 2021
$477k
ONE FRENCH FIBER OPTIC PRESSURE MICROTRANSDUCERR41HL053028 · NHLBI · OPTRAND, INC. · PI WLODARCZYK, MAREK T · 1994 to 1994
–
NHLBI NIH HHS R00 HL139996NHLBI NIH HHS R00HLI39996NHLBI NIH HHS R01 HL130796NHLBI NIH HHS R01 HL144599NHLBI NIH HHS R35 HL144481NHLBI NIH HHS R56 HL155055NHLBI NIH HHS R56HLI53028NHLBI NIH HHS UH3 HL145266
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Idiopathic Pulmonary FibrosisMicrobiotaHumansLungThorax

Identifiers

PMID35446241
PMCPMC9887421
OpenAlexW4224233593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.