Evidence map›Paper›PMID 35446133›Full record

ArticleAntimicrobial agents and chemotherapy2022

The Cationic Antimicrobial Peptide Activity of Lysozyme Reduces Viable

Candace N Rouchon, Joann Harris, Zahra Zubair-Nizami, Arielle J Weinstein, Mohammad Roky, Kristi L Frank

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. The Impact ofPathogens (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. The Antimicrobial Peptide AMP-17 Derived fromAntibiotics (Basel, Switzerland) · 2022
    Article
  11. Disruption of theJournal of bacteriology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Candace N RouchonDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciencesgrid.265436.0, Bethesda, Maryland, USA.
Joann HarrisDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciencesgrid.265436.0, Bethesda, Maryland, USA.
Zahra Zubair-NizamiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciencesgrid.265436.0, Bethesda, Maryland, USA.
Arielle J WeinsteinDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciencesgrid.265436.0, Bethesda, Maryland, USA.
Mohammad RokyDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciencesgrid.265436.0, Bethesda, Maryland, USA.
Kristi L FrankDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciencesgrid.265436.0, Bethesda, Maryland, USA.ORCID 0000-0003-0050-3380
Henry M. Jackson Foundation · USUniformed Services University of the Health Sciences · US

Funding

Role of the enterococcal site 2 protease in biofilm formation, adaptation, and host-pathogen interactionsR01AI141961 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI FRANK, KRISTI L · 2019 to 2023
$1.9M
HHS | National Institutes of Health (NIH) R01AI141961NIAID NIH HHS R01 AI141961
6 · The paper itself

Abstract

Enterococcus faecalis, a leading cause of health care-associated infections, forms biofilms and is resistant to many antimicrobial agents. Planktonic-phase E. faecalis is resistant to high concentrations of the enzyme lysozyme, which catalyzes the hydrolysis of

Indexed as

Enterococcus faecalisMuramidaseAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesBiofilmsPlanktonAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesMuramidasebiofilm-associated infectionCAMP activitycationic antimicrobial peptidehealthcare-associated infectioninnate immunitymuramidasenovel therapeuticspeptidoglycanprosthetic device infectionwound infection

Identifiers

PMID35446133
PMCPMC9112908
OpenAlexW4224222536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.