Evidence map›Paper›PMID 35446127›Full record

ArticlemBio2022

Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum

Rory Hennell James, Justin C Deme, Alicia Hunter, Ben C Berks, Susan M Lea

Abstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Tetrameric PilZ protein stabilizes stator ring in complex flagellar motor and is required for motility inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Advances in the type IX secretion system: an exploration focusing onCurrent research in microbial sciences · 2025
    Review
  8. Article
  9. Structure-function analysis of PorXScientific reports · 2024
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rory Hennell JamesSir William Dunn School of Pathology, University of Oxfordgrid.4991.5, Oxford, United Kingdom.ORCID 0000-0001-9009-9726
Justin C DemeSir William Dunn School of Pathology, University of Oxfordgrid.4991.5, Oxford, United Kingdom.ORCID 0000-0001-8811-9871
Alicia HunterSir William Dunn School of Pathology, University of Oxfordgrid.4991.5, Oxford, United Kingdom.ORCID 0000-0001-8850-7436
Ben C BerksDepartment of Biochemistry, University of Oxfordgrid.4991.5, Oxford, United Kingdom.ORCID 0000-0001-9685-4067
Susan M LeaSir William Dunn School of Pathology, University of Oxfordgrid.4991.5, Oxford, United Kingdom.ORCID 0000-0001-9287-8053

Funding

Structural biology of host-pathogen interactionsZIABC012043 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LEA, SUSAN MARY · 2021 to 2025
$6.9M
Wellcome TrustWellcome Trust 107929/Z/15/ZWellcome Trust 219477/Z/19/ZWellcome Trust (WT) 102164/Z/13/Z
6 · The paper itself

Abstract

Gliding motility using cell surface adhesins, and export of proteins by the type IX secretion system (T9SS) are two phylum-specific features of the Bacteroidetes. Both of these processes are energized by the GldLM motor complex, which transduces the proton motive force at the inner membrane into mechanical work at the outer membrane. We previously used cryo-electron microscopy to solve the structure of the GldLM motor core from Flavobacterium johnsoniae at 3.9-Å resolution (R. Hennell James, J. C. Deme, A. Kjaer, F. Alcock, et al., Nat Microbiol 6:221-233, 2021, https://dx.doi.org/10.1038/s41564-020-00823-6). Here, we present structures of homologous complexes from a range of pathogenic and environmental

Indexed as

Bacterial ProteinsBacterial Secretion SystemsBacteroidetesAdhesins, BacterialCryoelectron MicroscopyAdhesins, BacterialBacterial ProteinsBacterial Secretion SystemsBacteroidetesmotilityprotein secretionstructural biologytype IX secretion

Identifiers

PMID35446127
PMCPMC9239094

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.