Evidence map›Paper›PMID 35446110›Full record

ArticleThe Journal of urology2022

Differences in the Prevalence of Nocturnal Polyuria in the U.S. by Definition: Results from the Epidemiology of Nocturnal Polyuria Study.

J L H Ruud Bosch, Christopher R Chapple, Elizabeth R Mueller, Matt T Rosenberg, Bilal Chughtai, Kristian Juul, Karin S Coyne, Fredrik L Andersson, Elizabeth D Bacci, Jason C Simeone and 1 more

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04125186 (Epidemiology and Burden of Nocturia Due to Nocturnal Polyuria in the United States), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04125186 completednot on this map

Epidemiology and Burden of Nocturia Due to Nocturnal Polyuria in the United States: The EpiNP Study

TypeobservationalSponsorFerring PharmaceuticalsRan2019 to 2020Enrolled10,190ConditionsNocturnal PolyuriaArmsBaseline EpiNP survey, Bladder diary, Testing of EpiNP baseline survey, bladder diary and a qualitative interview, No other intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Nocturnal polyuria in women: results from the EpiNP study.International urogynecology journal · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

J L H Ruud BoschFranciscus G&V Hospital, Rotterdam, the Netherlands.
Christopher R ChappleUniversity of Sheffield, Sheffield, UK.
Elizabeth R MuellerLoyola University, Maywood, Illinois.
Matt T RosenbergMid Michigan Health Center, Jackson, Michigan.
Bilal ChughtaiWeill Cornell Medicine, New York, New York.
Kristian JuulFerring Pharmaceuticals Inc., Copenhagen, Denmark.
Karin S CoyneEvidera, Bethesda, Maryland.
Fredrik L AnderssonFerring Pharmaceuticals Inc., Copenhagen, Denmark.
Elizabeth D BacciEvidera, Seattle, Washington.
Jason C SimeoneEvidera, Waltham, Massachusetts.
Jeffrey P WeissSUNY Downstate Health Sciences University, Brooklyn, New York.
Ithaka Harbors · USFerring Pharmaceuticals (Denmark) · DKCornell University · USSint Franciscus Gasthuis · NLSUNY Downstate Health Sciences University · USUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevalence data on nocturnal polyuria (NP), nocturia caused by overproduction of urine during sleep, is primarily limited to men and varies by NP definition. This U.S.-representative epidemiological study of men and women ≥30 years old assessed the prevalence of NP. MATERIALS AND

methodsConsenting participants completed the baseline EpiNP (Epidemiology of Nocturnal Polyuria) survey (eg Lower Urinary Tract Symptoms Tool, comorbidities). All reporting ≥2 voids/night and a target of 100 random respondents reporting 0 or 1 void/night were asked to complete 3-day bladder diaries. NP was defined as nocturnal polyuria index (NPI) >0.33 (NPI33) and nocturnal urine production >90 ml/hour (NUP90). Extrapolated prevalence was stratified by sex and subgroups: idiopathic (without underlying causes), associated with overactive bladder (NPOAB), bladder outlet obstruction (NPBOO; men) and comorbidities. Voided volumes and timing, including first uninterrupted sleep period, were assessed by subgroup.

resultsA total of 10,190 individuals completed the baseline survey; mean age (range) was 54.4 (30-95). A total of 3,938 individuals were invited to complete the diary; 1,763 (49.3%) completed 3-day bladder diaries. Urine production (maximum nighttime volume, total volume, nocturnal urine production, nocturia index) was higher in both men and women with idiopathic NP and comorbidities. The median number of nighttime voids was greatest for NPBOO in men and NPOAB in women. Bother associated with nighttime voiding differed by NP subgroup but was highest in NPBOO for men (NPI33: 69.6%; NUP90: 71.1%) and NPOAB for women (NPI33: 67.5%; NUP90: 66.0%).

conclusionsThis population-based NP prevalence study including men and women characterizes NP subgroups and provides insights into nocturia treatment by emphasizing factors influencing urine production versus factors influencing bladder capacity.

Indexed as

NocturiaUrinary Bladder, OveractiveAdultFemaleHumansMalePolyuriaPrevalenceUrinationcross-sectional studiesepidemiologynocturiapolyuriaprevalence

Identifiers

PMID35446110
PMCPMC12721616
OpenAlexW4224292152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.