Evidence map›Paper›PMID 35445945›Full record

ArticleJournal of nephrology2022

Kinetics of human leukocyte antigen receptor HLA-DR

Désirée Tampe, Samy Hakroush, Lorenz Biggemann, Martin Sebastian Winkler, Björn Tampe

Open access · hybridAbstract read
In one paragraph

Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Désirée TampeDepartment of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany.
Samy HakroushInstitute of Pathology, University Medical Center Göttingen, Göttingen, Germany.
Lorenz BiggemannInstitute of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Martin Sebastian WinklerDepartment of Anesthesiology, Emergency and Intensive Care Medicine, University Medical Center Göttingen, Göttingen, Germany.
Björn TampeDepartment of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany. bjoern.tampe@med.uni-goettingen.de.ORCID 0000-0002-4357-9863
Universitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is characterized by small vessel inflammation and the presence of autoantibodies against cytoplasmic proteases, most often proteinase-3 and myeloperoxidase. Peripheral blood monocytes are an important source of local macrophage accumulation within parenchymal organs, as evidenced by their presence in early lesions in ANCA-associated glomerulonephritis. Major histocompatibility complex (MHC) II cell surface receptor human leukocyte antigen receptor (HLA-DR) allows antigen presentation to T cells and is crucial for the initiation of an immune response. We herein report HLA-DR abundance in AAV and the kinetics of HLA-DR

Indexed as

Antibodies, Antineutrophil CytoplasmicAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisCyclophosphamideHLA AntigensHLA-DR AntigensHumansKineticsMonocytesRemission InductionRituximabT-LymphocytesAntibodies, Antineutrophil CytoplasmicCyclophosphamideHLA AntigensHLA-DR AntigensRituximabANCA-associated vasculitis (AAV)Anti-neutrophil cytoplasmic antibody (ANCA)Human leukocyte antigen receptor (HLA-DR)Remission induction

Identifiers

PMID35445945
PMCPMC9107415
OpenAlexW4224217724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.