Evidence map›Paper›PMID 35445789›Full record

SynthesisInternational wound journal2022

A meta-analysis showing the effect of surgical site wound infections and associated risk factors in neonatal surgeries.

Mohamed A Abdelgawad, Della G T Parambi, Mohammed M Ghoneim, Nasser Hadal Alotaibi, Abdulaziz Ibrahim Alzarea, Abdullah S Alanazi, Ahmed Hassan, Sara M Tony, Mohamed Ea Abdelrahim

RetractedOpen access · goldAbstract readMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in International wound journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mohamed A AbdelgawadDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Della G T ParambiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Mohammed M GhoneimDepartment of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah, Saudi Arabia.
Nasser Hadal AlotaibiDepartment of clinical pharmacy, College of pharmacy, Jouf university Sakaka, Al Jouf, Saudi Arabia.
Abdulaziz Ibrahim AlzareaDepartment of clinical pharmacy, College of pharmacy, Jouf university Sakaka, Al Jouf, Saudi Arabia.
Abdullah S AlanaziDepartment of clinical pharmacy, College of pharmacy, Jouf university Sakaka, Al Jouf, Saudi Arabia.
Ahmed HassanClinical Pharmacy Department, Faculty of Pharmacy, University of Sadat City (USC), Sadat City, Egypt.
Sara M TonyClinical pharmacy department, Beni-suef specialized hospital, Beni-Suef, Egypt.
Mohamed Ea AbdelrahimDepartment of Clinical Pharmacy, Faculty of Pharmacy, Beni-Suef, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0003-0227-8404
Jouf University · SABeni-Suef University · EGAlfaisal University · SAUniversity of Sadat City · EG

Funding

Al Maarefa University Riyadh, Saudi Arabia TUMA-Project -2021-6
6 · The paper itself

Abstract

A meta-analysis was performed to assess the effect of surgical site wound infections and risk factors in neonates undergoing surgery. A systematic literature search up to January 2022 incorporated 17 trials involving 645 neonates who underwent surgery at the beginning of the trial; 198 of them had surgical site wound infections, and 447 were control for neonates. The statistical tools like the dichotomous or continuous method used within a random or fixed-influence model to establish the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) to evaluate the risk factors and influence of surgical site wound infections in neonates undergoing surgery. Surgical site wound infections had significantly higher mortality with OR value 2.03 at 95% CI 1.40-2.95 with P-value <0.001, the longer length of hospital stay (MD, 31.88; 95% CI, 18.17-45.59, P < 0.001), and lower birthweight of neonates (MD, -0.30; 95% CI, -0.53 to -0.07, P = 0.01) compared with neonates with no surgical site wound infections undergoing surgery. However, no remarkable change was observed with surgical site wound infections in the gestational age at birth of neonates (MD, -0.70; 95% CI, -1.46 to 0.05, P = 0.07), and the preoperative antibiotic prophylaxis (OR, 1.28; 95% CI, 0.57-2.87, P = 0.55) compared with no surgical site wound infections for neonates undergoing surgery. Surgical site wound infections had significantly higher mortality, a longer length of hospital stay, and lower birthweight of neonates. However, they had no statistically significant difference in the gestational age at birth of neonates and the preoperative antibiotic prophylaxis compared with no surgical site wound infections for neonates undergoing surgery. Furthermore, evidence is needed to confirm the outcomes.

Indexed as

Antibiotic ProphylaxisSurgical Wound InfectionBirth WeightHumansInfant, NewbornLength of StayRisk Factorsgestational age at birth of neonateslength of hospital staypreoperative antibiotic prophylaxissurgical site wound infectionsthe birthweight of neonates

Identifiers

PMID35445789
PMCPMC9705165
OpenAlexW4224248643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.